188866-44-6

Basic information

• Product Name: 4-(4-Hydroxyphenyl)-(3s,4s)-3-Piperidinol
• Synonyms: 4-(4-Hydroxyphenyl)-(3s,4s)-3-Piperidinol
• CAS NO: 188866-44-6
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.2423
• Mol File: 188866-44-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 377.2°C at 760 mmHg
• Flash Point: 214.2°C
• Appearance: /
• Density: 1.229g/cm³
• Vapor Pressure: 2.32E-06mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 4-(4-Hydroxyphenyl)-(3s,4s)-3-Piperidinol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Hydroxyphenyl)-(3s,4s)-3-Piperidinol(188866-44-6)
• EPA Substance Registry System: 4-(4-Hydroxyphenyl)-(3s,4s)-3-Piperidinol(188866-44-6)

Safety Data

• Hazardous Substances Data: 188866-44-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H15NO2/c13-11-3-1-9(2-4-11)10-5-7-12(14)8-6-10/h1-4,10,13-14H,5-8H2

Upstream product

• 257928-43-1 (R)-4-(4-benzyloxy-phenyl)-1-(1-phenyl-ethyl)-1,2,3,6-tetrahydro-pyridine 
• 257938-64-0 (3R,4R)-4-(4-benzyloxy-phenyl)-1-((R)-1-phenyl-ethyl)-piperidin-3-ol 
• 6717-00-6 1-benzyl-4-(4-methoxy-phenyl)-piperidin-4-ol 
• 13314-69-7 1-benzyl-4-(4-methoxy-phenyl)-1,2,3,6-tetrahydro-pyridine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 104-92-7 1-bromo-4-methoxy-benzene 

Relevant articles and documents

Piperidine renin inhibitors: from leads to drug candidates

Non-peptidomimetic renin inhibitors of the piperidine type represent a novel structural class of compounds potentially free of the drawbacks seen with peptidomimetic compounds so far. Synthetic optimization in two structural series focusing on improvement

Substituted piperidines - Highly potent renin inhibitors due to induced fit adaptation of tile active site

The identification, synthesis and activity of a novel class of piperidine renin inhibitors is presented. The most active compounds show activities in the picomolar range and are among the most potent renin inhibitors ever identified.