188911-98-0

Basic information

• Product Name: 1-(trimethylsilyl)-3(R*,S*)-methoxy-4(S)-(benzyloxy)-1-pentyne
• CAS NO: 188911-98-0
• Molecular Weight: 276.451
• Mol File: 188911-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(trimethylsilyl)-3(R*,S*)-methoxy-4(S)-(benzyloxy)-1-pentyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(trimethylsilyl)-3(R*,S*)-methoxy-4(S)-(benzyloxy)-1-pentyne(188911-98-0)
• EPA Substance Registry System: 1-(trimethylsilyl)-3(R*,S*)-methoxy-4(S)-(benzyloxy)-1-pentyne(188911-98-0)

Safety Data

• Hazardous Substances Data: 188911-98-0(Hazardous Substances Data)

Upstream product

• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 77-78-1 dimethyl sulfate 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 149885-10-9 [(1R,2S)-2-((S)-1-Benzyloxy-ethyl)-1-methyl-but-3-ynyl]-carbamic acid tert-butyl ester 
• 162612-26-2 2(R),4(S)-dimethyl-3(R)-ethynyl-γ-butyrolactone 
• 145072-02-2 2-[(2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-pent-4-ynoylamino]-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylic acid methyl ester 
• 145072-06-6 2-[(3R,4R)-3-((S)-1-Benzyloxy-ethyl)-4-methyl-2-methylene-5-oxo-pyrrolidin-1-yl]-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylic acid methyl ester 
• 145071-98-3 (2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-pent-4-ynoic acid 
• 149836-93-1 3-[(2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-5-trimethylsilanyl-pent-4-ynoyl]-oxazolidin-2-one 

Relevant articles and documents

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Chiral nonracemic acetylenic acids of general structure 11, prepared using the Schreiber modification of the Nicholas reaction, have been converted to β-amino acid derivatives of type 12 by a two-step sequence involving Curtius rearrangement followed by o