145072-02-2

Upstream product

• 122181-86-6 1-carbomethoxy-2-amino-4,5,6,7-tetrahydro-2H-isoindole 
• 145071-98-3 (2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-pent-4-ynoic acid 
• 149836-92-0 (S)-3-[(2R,3R)-3-((S)-1-Benzyloxy-ethyl)-2-methyl-5-trimethylsilanyl-pent-4-ynoyl]-4-isopropyl-oxazolidin-2-one 
• 188911-98-0 1-(trimethylsilyl)-3(R*,S*)-methoxy-4(S)-(benzyloxy)-1-pentyne 
• 122181-84-4 1-carbomethoxy-2-phthalimido-4,5,6,7-tetrahydro-2H-isoindole 
• 122181-81-1 2-phthalimido-4,5,6,7-tetrahydro-2H-isoindole 
• 81445-44-5 (S)-2-(benzyloxy)propanal 
• 51555-65-8 cyclohexane-1,2-dicarbaldehyde 
• 15753-50-1 cis-1,2-cyclohexanedimethanol 

Downstream Products

• 145072-06-6 2-[(3R,4R)-3-((S)-1-Benzyloxy-ethyl)-4-methyl-2-methylene-5-oxo-pyrrolidin-1-yl]-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Studies on the Synthesis of Phytochrome and Related Tetrapyrroles. Dihydropyrromethenones by Photochemical Rearrangement of N-Pyrrolo Enamides

Dihydropyrromethenone 67b, a potential precursor for the synthesis of phytochrome 1, has been prepared in enantiomerically pure form beginning with N-aminopyrrole 64 and the acetylenic acid 62b. The key step involved a 3,5-sigmatropic rearrangement of N-pyrrolo enamide 66b.

Tetrapyrroles. III. Homochiral dihydropyrromethenones from N-aminopyrroles and acetylenic acids

Dihydropyrromethenone 29, a potential precursor for the synthesis of Phytochrome (8), Phycocyanin (9) and Phycoerythrin (10), has been prepared in homochiral form from pyrrolohydrazide 27 by a sequence involving F-induced 5-exo-dig cyclization to afford enamide 28, followed by photochemical 3,5-sigmatropic rearrangement.