188918-74-3

Basic information

• Product Name: 2-Pyridinecarbonitrile,5-cyclopropyl-(9CI)
• Synonyms: 2-Pyridinecarbonitrile,5-cyclopropyl-(9CI);5-cyclopropylpicolinonitrile
• CAS NO: 188918-74-3
• Molecular Formula: C₉H₈N₂
• Molecular Weight: 144.176
• Product Categories: PYRIDINE
• Mol File: 188918-74-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Pyridinecarbonitrile,5-cyclopropyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarbonitrile,5-cyclopropyl-(9CI)(188918-74-3)
• EPA Substance Registry System: 2-Pyridinecarbonitrile,5-cyclopropyl-(9CI)(188918-74-3)

Safety Data

• Hazardous Substances Data: 188918-74-3(Hazardous Substances Data)

Upstream product

• 89809-64-3 2-cyano-5-chloropyridine 
• 411235-57-9 cyclopropylboronic acid 
• 925430-09-7 tricyclopropylbismuthane 
• 97483-77-7 2-Cyano-5-bromopyridine 

Downstream Products

• 1073428-41-7 (5-cyclopropylpyridin-2-yl)methanamine 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The problem of the present invention is to provide a compound having a PDE2A inhibitory action, and useful as a prophylactic or therapeutic drug for schizophrenia, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

2-Cyanophenyl fused heterocyclic compounds, and compositions and uses thereof

Fused heterocyclic compounds are provided according to formula 1: where R1, R2, R3, and m are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

Palladium-catalyzed cross-coupling reaction of tricyclopropylbismuth with aryl halides and triflates

(Chemical Equation Presented) The palladium-catalyzed cross-coupling reaction of tricyclopropylbismuth with aryl and heterocyclic halides and triflates is reported. The reaction tolerates numerous functional groups and does not require anhydrous conditions. The method was successfully extended to the cross-coupling of triethylbismuth.