189105-30-4

Upstream product

• 100-39-0 benzyl bromide 
• 163125-38-0 (1'S,2'S)-Ethyl 3,4-O-(1',2'-dimethoxycyclohexane-1',2'-diyl)-1-thio-α-D-mannopyranoside 
• 765-87-7 cyclohexane-1,2-dione 
• 171192-29-3 (1R,3R,4S,4aR,8aS,9aR,10aS)-1-(tert-Butyl-diphenyl-silanyloxymethyl)-3-ethylsulfanyl-8a,10a-dimethoxy-decahydro-2,9,10-trioxa-anthracen-4-ol 
• 163125-34-6 1,1,2,2-tetramethoxycyclohexane 
• 7473-36-1 ethyl 1-thio-α-D-mannopyranoside 
• 400835-46-3 ((1R,3R,4S,4aS,8aS,9aR,10aS)-4-Benzyloxy-3-ethylsulfanyl-8a,10a-dimethoxy-decahydro-2,9,10-trioxa-anthracen-1-ylmethoxy)-tert-butyl-diphenyl-silane 

Downstream Products

• 400835-47-4 ethyl-2-O-benzyl-3,4-O-[1',2'-dimethoxycyclohexan-1',2'-diyl]-6-O-isobutyl-1-thio-α-D-mannopyranoside 
• 1054624-09-7 (1S,3R,4S,4aS,8aS,9aS,10aS)-4-Benzyloxy-3-ethylsulfanyl-8a,10a-dimethoxy-decahydro-2,9,10-trioxa-anthracene-1-carbaldehyde 
• 713090-28-9 (1R,3R,4S,4aS,8aS,9aR,10aS)-4-Benzyloxy-3-ethylsulfanyl-8a,10a-dimethoxy-1-(3-methyl-butyl)-decahydro-2,9,10-trioxa-anthracene 
• 647030-06-6 (1R,3R,4S,4aS,8aS,9aR,10aS)-4-Benzyloxy-3-ethylsulfanyl-1-isobutyl-8a,10a-dimethoxy-decahydro-2,9,10-trioxa-anthracene 
• 647030-05-5 α-D-manno-oct-6-enopyranoside, ethyl-6,7,8-trideoxy-2-O-benzyl-3,4-O-[1',2'-dimethoxycyclohexan-1',2'-diyl]-7-methyl-1-thio 
• 713090-27-8 α-D-manno-non-6-enopyranoside, ethyl-6,7,8,9-tetradeoxy-2-O-benzyl-3,4-O-[1',2'-dimethoxycyclohexan-1',2'-diyl]-8-methyl-1-thio 
• 647030-03-3 (2R,3S,4S,5S,6R)-5-Benzyloxy-6-ethylsulfanyl-2-isopropoxymethyl-tetrahydro-pyran-3,4-diol 
• 400835-48-5 (2R,3S,4S,5S,6R)-5-Benzyloxy-6-ethylsulfanyl-2-isobutoxymethyl-tetrahydro-pyran-3,4-diol 
• 647029-75-2 ethyl-2-O-benzyl-3,4-O-[1',2'-dimethoxycyclohexan-1',2'-diyl]-6-O-isopropyl-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

Chemoselective o-benzylation of the propargylic hydroxy group in polyols

We have discovered the highly chemoselective benzylation of propargylic hydroxy groups in the presence of other hydroxy groups under very usual conditions involving benzyl bromide and sodium hydroxide in DMF at room temperature. This methodology has a hig

Synthesis and Structure - Activity Relationship of Mannose-Based Peptidomimetics Selectively Blocking Integrin α4β7 Binding to Mucosal Addressin Cell Adhesion Molecule-1

As part of our ongoing research in the development of α4β7 integrin antagonists, we are interested in peptidomimetics based on a rigid scaffold to allow the display of essential side chains in a suitable binding conformation while eliminating backbone ami

Design, synthesis, and biological evaluation of α4β1 integrin antagonists based on β-D-mannose as rigid scaffold

A cyclic peptide role model was used for the design and synthesis of a new class of biologically active and α4-selective integrin antagonists (e.g. 1) based on β-D-mannose. These carbohydrate-based peptidomimetics were synthesized to include th

Preparation, structure, derivatisation and NMR data of cyclohexane-1,2-diacetal protected carbohydrates

Acid catalysed reaction of monosaccharides with 1,1,2,2-tetramethoxycyclohexane results in selective protection of vicinal, diequatorial, diol functionality as a cyclohexane-1,2-diacetal (CDA). This new methodology complements classical cyclic acetal prot