189231-36-5Relevant academic research and scientific papers
Clean and efficient microwave-solvent-free conversion of homochiral amines, α-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives
Aydogan, Feray,Demir, Ayhan S.
, p. 3019 - 3023 (2007/10/03)
Efficient synthesis of 1,2-disubstituted homochiral pyrroles has been achieved by a two-component coupling of chloroenones and amine compounds on the surface of silica gel without any solvent under microwave irradiation.
Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives
Demir,Akhmedov,Sesenoglu,Alptuerk,Apaydin,Gercek,Ibrahimzade
, p. 1162 - 1167 (2007/10/03)
The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.
Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-methylpyrrole derivatives
Demir, Ayhan S.,Akhmedov, Idris M.,Tanyeli, Cihangir,Gercek, Zuhal,Gadzhili, Raik A.
, p. 753 - 757 (2007/10/03)
5-Chloro-3-penten-2-one reacts with the amino group of homochiral amines, amino alcohols, amino acid esters to form corresponding 2-pyrrole derivatives in good yield and without racemization.
