189266-03-3

Basic information

• Product Name: 1H-Indole, 7-bromo-1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 189266-03-3
• Molecular Formula: C15H12BrNO2S
• Molecular Weight: 350.236
• Mol File: 189266-03-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 7-bromo-1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 7-bromo-1-[(4-methylphenyl)sulfonyl]-(189266-03-3)
• EPA Substance Registry System: 1H-Indole, 7-bromo-1-[(4-methylphenyl)sulfonyl]-(189266-03-3)

Safety Data

• Hazardous Substances Data: 189266-03-3(Hazardous Substances Data)

Upstream product

• 51417-51-7 7-bromo-1H-indole 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 280752-68-3 7-bromo-1-methylindole 
• 51417-51-7 7-bromo-1H-indole 
• 189266-05-5 2-Acetylamino-3-[7-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-propionic acid ethyl ester 

Relevant articles and documents

Electron Transfer Photoredox Catalysis: Development of a Photoactivated Reductive Desulfonylation of an Aza-Heteroaromatic Ring

Herein, we report a protocol for desulfonylation of aza-heteroaromatic rings via photoinduced electron transfer and hydrogen atom transfer. This general protocol has a wide substrate range and moderate to good yields. The utility of the method was demonstrated by the chemoselective desulfonylation of a molecule containing both an aliphatic and an aromatic sulfonamide. (Figure presented.).

BENZOTHIOPHENE SULFONAMIDES AND OTHER COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN

The present invention relates to benzothiophene sulfonamides and other compounds that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof.