189323-09-9

Basic information

• Product Name: N-Cbz-N,N-bis(2-bromoethyl)amine
• Synonyms: N-Cbz-N,N-bis(2-bromoethyl)amine;CarbaMic acid,N,N-bis(2-broMoethyl)-, phenylMethyl ester;2-BroMo-N-(2-broMoethyl)-N-Cbz-ethanaMine;Benzyl bis(2-bromoethyl)carbamate
• CAS NO: 189323-09-9
• Molecular Formula: C₁₂H₁₅Br₂NO₂
• Molecular Weight: 365.06
• Mol File: 189323-09-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 402.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.619±0.06 g/cm3(Predicted)
• PKA: -1.85±0.70(Predicted)
• CAS DataBase Reference: N-Cbz-N,N-bis(2-bromoethyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cbz-N,N-bis(2-bromoethyl)amine(189323-09-9)
• EPA Substance Registry System: N-Cbz-N,N-bis(2-bromoethyl)amine(189323-09-9)

Safety Data

• Hazardous Substances Data: 189323-09-9(Hazardous Substances Data)

Usage

General Description

N-Cbz-N,N-bis(2-bromoethyl)amine is a chemical compound with the molecular formula C16H20Br2N2O2. It is a bis(2-bromoethyl) derivative of Cbz-protected amine, typically used in organic synthesis and pharmaceutical research. N-Cbz-N,N-bis(2-bromoethyl)amine is a white to off-white crystalline solid with a molecular weight of 412.15 g/mol. Its main application is as a reagent in the synthesis of various organic compounds, and it can also be used as a building block in the preparation of complex molecular structures. N-Cbz-N,N-bis(2-bromoethyl)amine should be handled and used with appropriate safety precautions, as it may pose health and environmental hazards.

Upstream product

• 501-53-1 benzyl chloroformate 
• 70782-12-6 N-benzyloxycarbonyldiethanolamine 
• 43204-63-3 bis(2-bromoethyl)amine hydrobromide 

Downstream Products

• 951744-37-9 methyl 1-benzyloxycarbonyl-4-(4,5-bis(4-methoxyphenyl)oxazol-2-yl)-4-piperidinecarboxylate 
• 951744-84-6 1-benzyloxycarbonyl-4-(4,5-bis(4-methoxyphenyl)oxazol-2-yl)-4-hydroxymethylpiperidine 
• 951744-85-7 4-acetoxymethyl-1-benzyloxycarbonyl-4-(4,5-bis(4-methoxyphenyl)oxazol-2-yl)piperidine 
• 25070-74-0 1-benzyloxycarbonylpyrrolidine 
• 362703-33-1 C₁₆H₁₈N₂O₄ 

Relevant articles and documents

Nickel-catalyzed reductive cyclization of alkyl dihalides

The reductive coupling protocol to intramolecular cyclization of dihaloalkanes is presented. It leads to five- and six-membered rings, with the former being more efficient. The incorporation of secondary alkyl halides generally promotes coupling efficiency. To the best of our knowledge, this is the first catalytic ring-closure reaction arising from dihaloalkanes under chemical reductive conditions.

Antiadhesive piperidine-and pyrrolidinecarboxylic acids

The invention relates to conjugates which consist of mono- or polycarboxylated piperidine or pyrrolidine derivatives and pyranoses, furanoses or polyalcohols linked via a chain or a cyclic system. The carboxyl groups of the piperidine derivatives can eith