189333-46-8

Basic information

• Product Name: 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile
• Synonyms: 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile;2,4-Dioxo-9-(phenylmethyl)-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile;3,9-Diazaspiro[5.5]undecane-1,5-dicarbonitrile, 2,4-dioxo-9-(phenylMethyl)-;9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile(WX102687)
• CAS NO: 189333-46-8
• Molecular Formula: C₁₈H₁₈N₄O₂
• Molecular Weight: 322.36
• Mol File: 189333-46-8.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 613.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.30
• Storage Temp.: 2-8°C
• PKA: 16.50±0.60(Predicted)
• CAS DataBase Reference: 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile(189333-46-8)
• EPA Substance Registry System: 9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile(189333-46-8)

Safety Data

• Hazardous Substances Data: 189333-46-8(Hazardous Substances Data)

Usage

General Description

9-benzyl-2,4-dioxo-3,9-diazaspiro[5.5]undecane-1,5-dicarbonitrile is a specialized organic chemical compound that belongs to the class of spirans, more specifically, the spirodihydrofurans. Spirans, including this specific compound, are part of a larger class of organic compounds which also exhibit bicyclic structural properties, meaning they consist of two connected ring structures. While there isn't a lot of specific information available about this chemical, general properties like melting point, boiling point, and solubility could be expected as per its structural configuration. Given its complex structure, this compound is likely used in advanced scientific research and could have potential applications in drug synthesis or material science.

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 1176981-06-8 1'-benzyl-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,4'-piperidine]-2,4,6,8-tetraone 
• 13323-40-5 3-benzyl-9-methyl-3,9-diaza-spiro[5.5]undecane 
• 1001054-49-4 3-benzyl-9-cyclobutyl-3,9-diazaspiro[5.5]undecane 
• 189333-49-1 3-benzyl-3,9-diazaspiro[5.5]undecane 
• 929302-01-2 tert-butyl 9-benzyl-3,9-diazaspiro[5.5]undecane-3-carboxylate 
• 170229-04-6 1-t-Butoxycarbonylpiperidine-4,4-diethanol 
• 160133-32-4 ethyl 2-[1-benzyl-4-(2-ethoxy-2-oxoethyl)-4-piperidyl]acetate 
• 189333-48-0 9-benzyl-3,9-diazaspiro[5.5]undecane-2,4-dione 
• 769901-73-7 2,2'-(1-benzylpiperidine-4,4-diyl)diacetic acid 

Relevant articles and documents

3,9- DIAZASPIRO[5,5] UNDECANE COMPOUND AS FLT3 AND AXL INHIBITORS

Disclosed in the present invention is a novel compound as FLT3 and AXL inhibitors. Sepcifically, disclosed are a compound represented by fomula (I) and a pharmacologically acceptable salt thereof.

Polymorphism of novel spiroarylphosphine oxide

The invention relates to a polymorphic substance of a compound (2-((5-chloro-2-((2-methoxyl-4-(9-methyl-3,9-diaza-sprio[5.5]hendecane-3-yl)phenyl)amino)pyrimidine-4-yl)amino)phenyl)dimethyl phosphineoxide (compound I). The invention further relates to a m

Spiro aryl phosphorus oxide or sulfide

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.