189333-48-0

Basic information

• Product Name: 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE
• Synonyms: 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE;3,9-Diazaspiro[5.5]undecane-2,4-dione, 9-(phenylmethyl)-;9-(phenylMethyl)-;9-(phenylmethyl)- 3,9-Diazaspiro[5.5]undecane-2,4-dione
• CAS NO: 189333-48-0
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.35
• Mol File: 189333-48-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 458.4°C at 760 mmHg
• Flash Point: 231°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 1.38E-08mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE(189333-48-0)
• EPA Substance Registry System: 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE(189333-48-0)

Safety Data

• Hazardous Substances Data: 189333-48-0(Hazardous Substances Data)

Usage

General Description

9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE is a chemical compound with potential applications in the field of medicine and pharmaceuticals. It belongs to the spiro compound family and contains a benzyl group and two nitrogen atoms in its spiro ring structure. 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE has the potential to exhibit various biological activities due to its unique chemical structure. It may be used in drug discovery and development as a potential pharmacophore for designing new drugs targeting various diseases. Furthermore, it may also have applications in organic synthesis and as a building block for the creation of other complex chemical compounds. Overall, 9-BENZYL-3,9-DIAZA-SPIRO[5.5]UNDECANE-2,4-DIONE holds promise for further exploration and research in both the pharmaceutical and chemical industries.

InChI:InChI=1/C16H20N2O2/c19-14-10-16(11-15(20)17-14)6-8-18(9-7-16)12-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,17,19,20)

Upstream product

• 1176981-06-8 1'-benzyl-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,4'-piperidine]-2,4,6,8-tetraone 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 769901-73-7 2,2'-(1-benzylpiperidine-4,4-diyl)diacetic acid 
• 189333-46-8 9-benzyl-2,4-dioxo-3,9-diazaspiro[5,5]undecane-1,5-dicarbonitrile 

Downstream Products

• 189333-49-1 3-benzyl-3,9-diazaspiro[5.5]undecane 
• 1338706-96-9 C₃₃H₃₉ClN₂O₅ 
• 13323-40-5 3-benzyl-9-methyl-3,9-diaza-spiro[5.5]undecane 
• 1001054-49-4 3-benzyl-9-cyclobutyl-3,9-diazaspiro[5.5]undecane 

Relevant articles and documents

3,9- DIAZASPIRO[5,5] UNDECANE COMPOUND AS FLT3 AND AXL INHIBITORS

Disclosed in the present invention is a novel compound as FLT3 and AXL inhibitors. Sepcifically, disclosed are a compound represented by fomula (I) and a pharmacologically acceptable salt thereof.

Polymorphism of novel spiroarylphosphine oxide

The invention relates to a polymorphic substance of a compound (2-((5-chloro-2-((2-methoxyl-4-(9-methyl-3,9-diaza-sprio[5.5]hendecane-3-yl)phenyl)amino)pyrimidine-4-yl)amino)phenyl)dimethyl phosphineoxide (compound I). The invention further relates to a m

Spiro aryl phosphorus oxide or sulfide

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.