189350-64-9

Basic information

• Product Name: (R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL
• Synonyms: (R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL;(R)-2,2,2-Trifluoro-1-phenylethylamine hydrochloride;(R)-2,2,2-Trifluoro-1-phenylethanaMine hydrochloride;(R)-2,2,2-trifluoro-1-phenylethanamine-HCl;(1R)-2,2,2-trifluoro-1-phenylethanamine,hydrochloride;(R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HYDROCHLRIDE
• CAS NO: 189350-64-9
• Molecular Formula: C8H9ClF3N
• Molecular Weight: 211.61
• Product Categories: pharmacetical
• Mol File: 189350-64-9.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 237.7 °C at 760 mmHg
• Flash Point: 97.6 °C
• Appearance: /
• Vapor Pressure: 0.0356mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(189350-64-9)
• EPA Substance Registry System: (R)-2,2,2-TRIFLUORO-1-PHENYLETHYLAMINE HCL(189350-64-9)

Safety Data

• Hazardous Substances Data: 189350-64-9(Hazardous Substances Data)

Usage

General Description

(R)-2,2,2-Trifluoro-1-phenylethylamine HCl is a chemical compound that belongs to the family of amines. It is a derivative of phenethylamine with a trifluoromethyl group attached to the alpha carbon. (R)-2,2,2-Trifluoro-1-phenylethylamine HCl is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a chiral auxiliary in asymmetric synthesis. The hydrochloride salt form of this compound is a white crystalline powder and is commonly used for ease of handling and storage. (R)-2,2,2-Trifluoro-1-phenylethylamine HCl is considered to be a valuable building block in organic synthesis due to its unique stereochemistry and reactivity.

InChI:InChI=1/C8H8F3N.ClH/c9-8(10,11)7(12)6-4-2-1-3-5-6;/h1-5,7H,12H2;1H/t7-;/m1./s1

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Relevant articles and documents

Diastereoselective addition of organomagnesium and organolithium reagents to chiral trifluoromethyl N-tert-butanesulfinyl hemiaminals

The asymmetric synthesis of trifluoromethylated tertiary and secondary carbinamines (α,α-dibranched and α-branched amines) was achieved by reaction of alkyl, aryl and allyl organomagnesium or organolithium reagents to trifluoromethyl N-tert-butanesulfinyl

METHOD FOR PRODUCING OPTICALLY ACTIVE TRIFLUOROMETHYL GROUP-CONTAINING AMINO ACID DERIVATIVE

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