189748-60-5

Basic information

• Product Name: Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester
• Synonyms: Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester
• CAS NO: 189748-60-5
• Molecular Weight: 538.755
• Mol File: 189748-60-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester(189748-60-5)
• EPA Substance Registry System: Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester(189748-60-5)

Safety Data

• Hazardous Substances Data: 189748-60-5(Hazardous Substances Data)

Upstream product

• 347362-38-3 2,5-dideoxy-2,5-epithio-3-O-benzyl-D-lyxofuranoside 
• 160882-25-7 3-O-benzyl-1-deoxy-4-thio-D-arabino-furanose 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 189748-59-2 ((2R,3S,4S)-3-Benzyloxy-4-fluoro-tetrahydro-thiophen-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 174833-54-6 (3S,4S,5R)-4-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-ol 
• 108-24-7 acetic anhydride 

Downstream Products

• 207671-67-8 1-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-D-arabino-pentofuranosyl)-5-ethyluracil 
• 207671-69-0 1-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-D-arabino-pentofuranosyl)-5-fluorouracil 
• 207671-70-3 1-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-D-arabino-pentofuranosyl)-5-fluorocytosine 
• 207671-75-8 9-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-α(and β)-D-arabino-pentofuranosyl)adenine 
• 197648-56-9 9-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-α(and β)-D-arabino-pentofuranosyl)-2,6-dichloropurine 
• 197648-59-2 9-(3-O-benzyl-5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-α(and β)-D-arabino-pentofuranosyl)-2,6-diaminopurine 
• 294867-98-4 5-(2-tert-butyldimethylsilyloxyethyl)-1-(5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-β-D-arabinopentofuranosyl)uracil 
• 294867-99-5 5-(2-tert-butyldimethylsilyloxyethyl)-1-(5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-α-D-arabinopentofuranosyl)uracil 
• 197648-58-1 9-(5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-β-D-arabino-pentofuranosyl)-2,6-dichloropurine 
• 197648-57-0 9-(5-O-(tert-butyldiphenylsilyl)-2-deoxy-2-fluoro-4-thio-α-D-arabino-pentofuranosyl)-2,6-dichloropurine 
• 294867-78-0 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-thiophen-2-yl]-4-hydroxy-5-iodo-1H-pyrimidin-2-one 
• 294867-80-4 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-thiophen-2-yl]-4-hydroxy-5-iodo-1H-pyrimidin-2-one 
• 294867-74-6 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-thiophen-2-yl]-5-ethyl-4-hydroxy-1H-pyrimidin-2-one 
• 294867-76-8 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-thiophen-2-yl]-5-ethyl-4-hydroxy-1H-pyrimidin-2-one 

Relevant articles and documents

Synthetic studies on 2'-substituted-4'-thiocytidine derivatives as antineoplastic agents

As potential antineoplastic agents, we have synthesized 4'-thioFAC and 4'-thiocytarazid by developing an alternative synthetic method. 4'-ThioFAC showed potent antineoplastic activities in vivo as well as in vitro.