347362-38-3

Upstream product

• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 18685-18-2 3-O-benzyl-1,2-5,6-O-diisopropylidene-α-D-glucofuranose 
• 22529-61-9 (1R)-1-((3aR,6S,6aR)-6-(benzyloxy)-2,2-dimethyltetrahydrofuro(2,3-d)(1,3)dioxol-5-yl)ethane-1,2-diol 
• 34370-91-7 3-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranose 
• 438576-28-4 methyl 3-O-benzyl-2,5-di-O-methanesulfonyl-D-furanoyl glucoside 

Downstream Products

• 160882-25-7 3-O-benzyl-1-deoxy-4-thio-D-arabino-furanose 
• 1054646-13-7 (2S,3S,4S)-3-Benzyloxy-4-hydroxy-tetrahydro-thiophene-2-carbaldehyde 
• 189748-74-1 Benzoic acid (2R,3S,4R,5R)-5-(4-acetylamino-2-oxo-2H-pyrimidin-1-yl)-4-azido-2-hydroxymethyl-tetrahydro-thiophen-3-yl ester 
• 189748-73-0 Benzoic acid (2R,3S,4R,5S)-5-(4-acetylamino-2-oxo-2H-pyrimidin-1-yl)-4-azido-2-hydroxymethyl-tetrahydro-thiophen-3-yl ester 
• 189748-65-0 Acetic acid (3R,4S,5R)-3-azido-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-2-yl ester 
• 189748-67-2 Benzoic acid (2R,3S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophen-3-yl ester 
• 189748-72-9 Benzoic acid (2R,3S,4R)-5-(4-acetylamino-2-oxo-2H-pyrimidin-1-yl)-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-thiophen-3-yl ester 
• 1054794-98-7 (2R,3S,4S)-3-Benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-thiophene 
• 189748-60-5 Acetic acid (3S,4S,5R)-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-tetrahydro-thiophen-2-yl ester 
• 189748-63-8 ((2R,3S,4R)-4-Azido-3-benzyloxy-tetrahydro-thiophen-2-ylmethoxy)-tert-butyl-diphenyl-silane 
• 189748-69-4 Benzoic acid (2R,3S,4R)-5-acetoxy-4-azido-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-thiophen-3-yl ester 

Relevant academic research and scientific papers

Synthesis and biological activities of 2'-modified 4'-thionucleosides

We have synthesized 4'-thioDMDC, 4'-thiogemcitabine, and 4'- thioarabinonucleosides, as potential antitumor and antiviral agents, originated from D-glucose. Biological activities of these compounds are also described.

Gram-level total synthesis method of sulfur onium salt type natural product neoponkoranol extracted from salacia plants

The invention belongs to the field of chemical synthesis and particularly relates to a gram-level total synthesis method of a sulfur onium salt type natural product neoponkoranol with hypoglycemic activity extracted from salacia plants. According to the m