18979-90-3

Basic information

• Product Name: 4-06-00-03013 (Beilstein Handbook Reference)
• CAS NO: 18979-90-3
• Molecular Formula: C₈H₉ClO
• Molecular Weight: 156.612
• Mol File: 18979-90-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-06-00-03013 (Beilstein Handbook Reference)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-06-00-03013 (Beilstein Handbook Reference)(18979-90-3)
• EPA Substance Registry System: 4-06-00-03013 (Beilstein Handbook Reference)(18979-90-3)

Safety Data

• Hazardous Substances Data: 18979-90-3(Hazardous Substances Data)

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 7647-01-0 hydrogenchloride 
• 56911-73-0 4-chloro-2-ethyl-1-methoxybenzene 
• 1216072-89-7 1-(5-chloro-2-methoxyphenyl)-1-ethanol 
• 6342-64-9 2-methoxy-5-chloroacetophenone 
• 925-90-6 ethylmagnesium bromide 
• 120-83-2 2,4-dichlorophenol 
• 876-27-7 4-chlorophenyl acetate 
• 75-03-6 ethyl iodide 
• 106-48-9 4-chloro-phenol 
• 90-00-6 o-Hydroxyethylbenzene 
• 64-17-5 ethanol 

Downstream Products

• 6964-28-9 (2-ethyl-4-chloro-phenoxy)-acetic acid 
• 53347-16-3 acetic acid-(2-ethyl-4-chloro-phenyl ester) 
• 53347-18-5 Buttersaeure-<4-chlor-2-aethyl-phenylester> 
• 53346-74-0 5-Chlor-2-hydroxy-3-aethylbenzylalkohol 
• 53347-25-4 Pentansaeure-<4-chlor-2-aethyl-phenylester> 
• 53347-26-5 Hexansaeure-<4-chlor-2-aethyl-phenylester> 
• 53346-88-6 4-Chlor-2-aethyl-6-(4-fluor-3-aethyl)-benzylphenol 
• 53346-82-0 4-Chlor-2-aethyl-6-cyclopentylphenol 
• 53346-83-1 4-Chlor-2-aethyl-6-cyclohexylphenol 
• 53346-89-7 4-Chlor-2-aethyl-6-(4-methoxy-3-aethyl)benzylphenol 
• 53347-03-8 4-chloro-2-ethyl-6-nitrophenol 
• 53346-86-4 4-Chlor-2-aethyl-6-(3,4-dichlor)-benzylphenol 
• 29848-96-2 4-Chloro-2-ethyl-6-benzylphenol 
• 53346-96-6 4-Chlor-2-(β-hydroxyaethylamino)methyl-6-aethylphenol 

Relevant articles and documents

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Chemical Compounds

The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I): or a pharmaceutically acceptable salt thereof, wherein Ar1, X, R1, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.

High ortho preference in Ni-catalyzed cross-coupling of halophenols with alkyl Grignard reagents

(Chemical Equation Presented) High preference of substitution at the position ortho to the hydroxy group was observed for Ni-catalyzed cross-coupling reactions of dihalophenols with alkyl Grignard reagents. Reactions of 2,4-dihalophenols, with various com