1899-40-7 Usage
Uses
Used in Pharmaceutical Synthesis:
5,6,7,8-Tetrahydroquinazoline-2,4-diamine is used as a key intermediate in the development of new pharmaceuticals for its ability to interact with various biological targets, contributing to the creation of potential therapeutic agents.
Used in Agrochemical Development:
In the agrochemical industry, 5,6,7,8-Tetrahydroquinazoline-2,4-diamine is utilized as a building block for the synthesis of compounds with pesticidal properties, leveraging its reactivity and structural attributes to enhance crop protection.
Used in Neurological Disorder Treatment:
5,6,7,8-Tetrahydroquinazoline-2,4-diamine is studied for its potential therapeutic applications in the treatment of neurological disorders, capitalizing on its capacity to engage with specific biological targets that may ameliorate disease symptoms or progression.
Used in Cancer Therapy:
5,6,7,8-Tetrahydroquinazoline-2,4-diamine is being investigated for its role in cancer treatment, with research focusing on its interaction with biological targets that could inhibit tumor growth or enhance the effectiveness of existing cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1899-40-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,9 and 9 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1899-40:
(6*1)+(5*8)+(4*9)+(3*9)+(2*4)+(1*0)=117
117 % 10 = 7
So 1899-40-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N4/c9-7-5-3-1-2-4-6(5)11-8(10)12-7/h1-4H2,(H4,9,10,11,12)
1899-40-7Relevant academic research and scientific papers
Pyrimidine Derivatives. II. New Synthesis and Reactions of 4-Amino-2-methylthiopyrimidine Derivatives
Sekiya, Tetsuo,Hiranuma, Hidetoshi,Uchide, Masayuki,Hata, Shunsuke,Yamada, Shun-Ichi
, p. 948 - 954 (2007/10/02)
4-Amino-2-methylthiopyrimidine derivatives (4) were synthesized by the cyclization of 3-cyano-2-methylisothiourea (2) with ketones (3).Oxidation of 4 produced 4-amino-2-methylsulfinyl or 2-methylsulfonylpyrimidine derivatives (7 or 8).Amination of 7 or 8 gave hypoglycemic 2-(1-piperazinyl)pyrimidines (1).Compounds 4 were converted to 4(3H)-pyrimidinone derivatives (12).Derivatives 1 were also synthesized via 12.Keywords - hypoglycemic drug; base-catalyzed cyclization; 3-cyano-2-methylisothiourea; 4-amino-2-methylthiopyrimidines; 4-amino-2-methylthio-5,6,7,8-tetrahydroquinazoline; 2-methylthio-4(3H)-pyrimidinones; 2-methylsulfinylpyrimidines amination; 2-methylsulfonylpyrimidines amination
