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2(5H)-Furanone, 3-[(5-fluoro-2-pyridinyl)oxy]-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

189954-64-1

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189954-64-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 189954-64-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,9,5 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 189954-64:
(8*1)+(7*8)+(6*9)+(5*9)+(4*5)+(3*4)+(2*6)+(1*4)=211
211 % 10 = 1
So 189954-64-1 is a valid CAS Registry Number.

189954-64-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(5-fluoropyridin-2-yl)oxy]-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one

1.2 Other means of identification

Product number -
Other names 3-(5-Fluoro-pyridin-2-yloxy)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:189954-64-1 SDS

189954-64-1Downstream Products

189954-64-1Relevant academic research and scientific papers

Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

Lau, Cheuk K.,Brideau, Christine,Chan, Chi Chung,Charleson, Stella,Cromlish, Wanda A.,Ethier, Diane,Yves Gauthier, Jacques,Gordon, Robert,Guay, Jocelyne,Kargman, Stacia,Li, Chun-Sing,Prasit, Petpiboon,Riendeau, Denis,Therien, Michel,Visco, Denise M.,Xu, Lijing

, p. 3187 - 3192 (2007/10/03)

A series of 3-heteroaryloxy-4-phenyl-2-(5H)-furanones were prepared and evaluated for their potency and selectivity as COX-2 inhibitors. This led to the identification of L-778,736 as a potent, orally active and selective inhibitor of the COX-2 enzyme.

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