18997-72-3

Basic information

• Product Name: [3-(Dimethylamino)propyl]dithiocarbamic acid
• Synonyms: [3-(Dimethylamino)propyl]dithiocarbamic acid;N-[3-(Dimethylamino)propyl]carbamodithioic acid
• CAS NO: 18997-72-3
• Molecular Formula: C₆H₁₄N₂S₂
• Molecular Weight: 178.3188
• Mol File: 18997-72-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 233.1°Cat760mmHg
• Flash Point: 94.8°C
• Appearance: /
• Density: 1.096g/cm³
• Vapor Pressure: 0.0568mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: [3-(Dimethylamino)propyl]dithiocarbamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(Dimethylamino)propyl]dithiocarbamic acid(18997-72-3)
• EPA Substance Registry System: [3-(Dimethylamino)propyl]dithiocarbamic acid(18997-72-3)

Safety Data

• Hazardous Substances Data: 18997-72-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14N2S2/c1-8(2)5-3-4-7-6(9)10/h3-5H2,1-2H3,(H2,7,9,10)

Upstream product

• 75-15-0 carbon disulfide 
• 109-55-7 1-amino-3-(dimethylamino)propane 

Downstream Products

• 1892-57-5 N-(3-dimethylaminopropyl)-N-ethylcarbodiimide 
• 27421-70-1 3-(dimethylamino)propyl isothiocyanate 
• 25952-53-8 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride 

Relevant articles and documents

PPAR-γ ligand —4, 5 -diazafluor - rhodanine conjugate as well as preparation method and anti-tumor application thereof

The invention discloses PPAR-γ ligand —4, 5 -diazafluor - rhodanine conjugate and a preparation method thereof, an anti-tumor application, 4, 5 -diazafluorene - rhodanine conjugates. The structure of R is YINQ - 1. , YINQ - 3 YINQ - 4. YINQ - 5 YINQ - 6 Y

1 - (3-dimethylamino-propyl) - 3-ethyl carbodiimide hydrochloride preparation method

The invention belongs to the field of organic chemical industry, and particularly relates to a preparation method of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride. The method comprises the following steps: enabling N,N'-dimethyl-1,3-propanediamine and carbon disulfide as raw materials to react in an organic solvent to generate an intermediate 1; enabling the intermediate 1 and ethyl chloroformate to react in the organic solvent, and preparing an intermediate 2 from triethylamine as an acid-binding agent; enabling the intermediate 2 and ethylamine to react in the organic solvent, so as to prepare an intermediate 3; adding a catalyst to the intermediate 3, oxidizing one time with an oxidant, so as to obtain a crude product 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, extracting and separating, so as to obtain an intermediate 4; and carrying out salt exchange reaction on the intermediate 4 and hydrochloride, so as to prepare the product 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride. The method has the advantages of relatively high conversion rate and relatively high total recovery rate and is simple to operate and suitable for industrial production.