190001-40-2

Basic information

• Product Name: 4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 1-BOC-4-CHLOROACETYL-PIPERAZINE;4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;4-(2-CHLORO-ACETYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-butyl 4-(chloroacetyl)piperazine-1-carboxylate;4-Chloroacetyl-piperazine-1-carboxylic acid;1-BOC-4-CHLOROACETYL-PIPERAZINE, 4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER >98%;tert-butyl 4-(2-chloroacetyl)piperazine-1-carboxylate;4-(Chloroacetyl)piperazine, N1-BOC protected
• CAS NO: 190001-40-2
• Molecular Formula: C₁₁H₁₉ClN₂O₃
• Molecular Weight: 262.73
• Product Categories: piperazines
• Mol File: 190001-40-2.mol
• Article Data: 33

Chemical Properties

• Melting Point: 99-100°C
• Boiling Point: 379.9°Cat760mmHg
• Flash Point: 183.6°C
• Appearance: /
• Density: 1.203g/cm³
• Vapor Pressure: 5.67E-06mmHg at 25°C
• Refractive Index: 1.501
• CAS DataBase Reference: 4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(190001-40-2)
• EPA Substance Registry System: 4-CHLOROACETYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(190001-40-2)

Safety Data

• Hazardous Substances Data: 190001-40-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H19ClN2O3/c1-11(2,3)17-10(16)14-6-4-13(5-7-14)9(15)8-12/h4-8H2,1-3H3

Upstream product

• 79-04-9 chloroacetyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 861359-74-2 diisopropylethyl amine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Downstream Products

• 1010925-33-3 tert-butyl 4-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetyl]-piperazine-1-carboxylate 
• 1380297-11-9 benzyl 4-(2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetyl)piperazine-1-carboxylate 
• 1380297-12-0 4-nitrophenyl 4-(2-(3-oxobenzo[d]isothiazol-2(3H)-yl)acetyl)piperazine-1-carboxylate 

Relevant articles and documents

Parallel synthesis of isatin-based serine protease inhibitors

The synthesis of N-functionalised isatins using parallel, solution synthesis is described. Functionalised polymers were employed as stoichiometric and catalytic reagents as well as purification media in the exercise, and the derivatives were screened against a panel of serine proteases; high percentage inhibition was observed in several cases. (C) 2000 Elsevier Science Ltd.

Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library

The therapeutic indications for monoamine oxidases A and B (MAO-A and MAO-B) inhibitors that have emerged from biological studies on animal and cellular models of neurological and oncological diseases have focused drug discovery projects upon identifying

Discovery of GPR183 Agonists Based on an Antagonist Scaffold

The G protein-coupled receptor GPR183/EBI2, which is activated by oxysterols, is a therapeutic target for inflammatory and metabolic diseases where both antagonists and agonists are of potential interest. Using the piperazine diamide core of the known GPR

NEW COMPOUNDS FOR TREATMENT OF DISEASES RELATED TO DUX4 EXPRESSION

The present invention relates to compounds for the treatment of diseases related to DUX4 expression, such as muscular dystrophies. It also relates to use of such compounds, or to methods of use of such compounds.