190071-23-9

Usage

InChI:InChI=1/C10H10INO3/c1-6(13)12-9-4-3-7(5-8(9)11)10(14)15-2/h3-5H,1-2H3,(H,12,13)

Upstream product

• 186581-53-3 diazomethane 
• 190071-24-0 4-acetylamino-3-iodo-benzoic acid 
• 19718-49-1 4-amino-3-iodobenzoic acid methyl ester 
• 108-24-7 acetic anhydride 
• 619-45-4 4-methoxycarbonyl aniline 
• 17012-22-5 methyl 4-acetamidobenzoate 
• 2122-63-6 4-amino-3-iodobenzoic acid 
• 150-13-0 4-amino-benzoic acid 

Downstream Products

• 190071-25-1 2-phenyl-1H-indole-5-carboxylic acid methyl ester 
• 1021165-74-1 2-(2,6-dichloro-phenyl)-1H-indole-5-carboxylic acid methyl ester 
• 6941-28-2 2-methyl-1,3-benzothiazole-6-carboxylic acid 
• 1246250-14-5 4-acetylamino-3-[4-(tetrahydro-pyran-2-yloxy)-but-1-ynyl]-benzoic acid methyl ester 
• 1246250-03-2 N-[4-formyl-2-(4-hydroxy-but-1-ynyl)-phenyl]-acetamide 
• 1246250-02-1 N-(4-hydroxymethyl-2-iodo-phenyl)-acetamide 
• 186801-00-3 4-methoxycarbonyl-2-(2-propenyl)acetanilide 

Relevant academic research and scientific papers

Monoprotected l-Amino Acid (l-MPAA), Accelerated Bromination, Chlorination, and Iodination of C(sp2)?H Bonds by Iridium(III) Catalysis

Halogenated arenes are important structural motifs commonly found in biologically active molecules and used for a variety of transformations in organic synthesis. Herein, we report the mono-protected l-amino acid (l-MPAA) accelerated iridium(III)-catalyzed halogenation of (hetero)anilides at room temperature. This reaction constitutes the first example of an iridium(III)/l-MPAA-catalyzed general halogenation of (hetero)arenes through C(sp2)?H activation. Furthermore, we demonstrate the potential utility of our method through its use in the synthesis of a quinolone derivative.

A General Copper Catalyst for Photoredox Transformations of Organic Halides

A broadly applicable copper catalyst for photoredox transformations of organic halides is reported. Upon visible light irradiation in the presence of catalytic amounts of [(DPEphos)(bcp)Cu]PF6 and an amine, a range of unactivated aryl and alkyl halides were shown to be smoothly activated through a rare Cu(I)/Cu(I)?/Cu(0) catalytic cycle. This complex efficiently catalyzes a series of radical processes, including reductions, cyclizations, and direct arylation of arenes.

Design and synthesis of 1-benzazepine derivatives by strategic utilization of Suzuki-Miyaura cross-coupling, aza-Claisen rearrangement and ring-closing metathesis

A new and simple methodology has been realized for the synthesis of 7-substituted 2,3,4,5-tetrahydro-1-benzazepine derivatives with Suzuki-Miyaura cross-coupling, aza-Claisen rearrangement and ring-closing metathesis (RCM) the key steps. Here, o-allylacet

METHOD OF TREATMENT

Method of of preventing or treating myocardial ischemia by inhibiting DGAT1 enzyme with a DGAT1 inhibitor compound.

Conjugate additions of o-iodoanilines and methyl anthranilates to acetylenic sulfones. A new route to quinolones including first syntheses of two alkaloids from the medicinal herb Ruta chalepensis

A novel synthesis of 2-substituted 4-quinolones was developed on the basis of the conjugate additions of appropriately ortho-substituted anilines to acetylenic sulfones followed by intramolecular acylation of the corresponding sulfone-stabilized anions. C

Solid-phase synthesis of indoles using the palladium-catalysed coupling of alkynes with iodoaniline derivatives

The solid-phase synthesis of indoles using Pd(0) catalysed coupling of alkynes with iodaniline derivatives is described. The reaction gives indoles in high yields with a wide range of alkynes.