19013-11-7

Basic information

• Product Name: 4-METHYL-3-NITROBENZAMIDE
• Synonyms: 3-NITRO-4-METHYLBENZAMIDE;4-METHYL-3-NITROBENZAMIDE;4-methyl-3-nitro-benzamid;3-NITRO-4-METHYLBENZOYL AMINE
• CAS NO: 19013-11-7
• Molecular Formula: C₈H₈N₂O₃
• Molecular Weight: 180.16
• EINECS: 242-752-4
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 19013-11-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 164-165°C
• Boiling Point: 291.7 °C at 760 mmHg
• Flash Point: 130.2 °C
• Appearance: /
• Density: 1.322 g/cm³
• Vapor Pressure: 0.00192mmHg at 25°C
• Refractive Index: 1.599
• BRN: 2102644
• CAS DataBase Reference: 4-METHYL-3-NITROBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-3-NITROBENZAMIDE(19013-11-7)
• EPA Substance Registry System: 4-METHYL-3-NITROBENZAMIDE(19013-11-7)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• RIDADR: 2811
• TSCA: Yes
• PackingGroup: III
• Hazardous Substances Data: 19013-11-7(Hazardous Substances Data)

Usage

General Description

4-Methyl-3-nitrobenzamide is a chemical compound with the molecular formula C8H8N2O3. It is a derivative of benzamide, with a methyl group and a nitro group attached to the benzene ring. 4-METHYL-3-NITROBENZAMIDE is commonly used in organic synthesis and research as a building block to create other chemical compounds. It has potential applications in pharmaceuticals, agrochemicals, and materials science. It can also be used as a reagent in chemical reactions and as a precursor for the synthesis of various organic compounds. 4-Methyl-3-nitrobenzamide is considered to be of moderate toxicity and should be handled with care in laboratory settings.

InChI:InChI=1/C8H8N2O3/c1-5-2-3-6(8(9)11)4-7(5)10(12)13/h2-4H,1H3,(H2,9,11)

Upstream product

• 41252-97-5 4-iodo-2-nitrotoluene 
• 444667-11-2 2-(4-carboxy-2-nitrophenyl)-acetic acid 
• 501-89-3 4-(carboxymethyl)benzoic acid 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 104-85-8 para-methylbenzonitrile 
• 619-55-6 para-methylbenzamide 
• 939-79-7 4-cyano-2-nitrotoluene 
• 96-98-0 4-methyl-3-nitrobenzoic acid 

Downstream Products

• 623155-52-2 C₁₁H₁₂N₂O₅ 
• 623155-51-1 C₁₁H₁₄N₂O₃ 
• 623155-49-7 C₁₁H₁₄N₂O₂ 
• 623154-45-0 C₂₂H₂₆N₆O₄ 
• 623154-44-9 C₂₂H₂₆N₆O₃ 
• 623155-50-0 C₁₁H₁₂N₂O₄ 
• 1401624-08-5 C₉H₆N₂O₄ 
• 836684-57-2 N-dimethylaminomethylene-4-methyl-3-nitro-benzamide 
• 61599-56-2 2-nitro-trans-stilbene-carboxylic acid-⁽⁴⁾-amide 
• 16533-71-4 3,5-dinitro-p-toluic acid 

Relevant articles and documents

Palladium on manganese ferrite: An efficient catalyst for one pot synthesis of primary amides from iodobenzene

Amidation of aryl iodide in one pot is reported using Pd-MnFe2O4 as a catalyst. The catalyst was characterized by various techniques such as XRD, FEG-SEM, EDS, TEM, BET surface area and ICP AES. K4[Fe(CN)6]is used as a non toxic cyanation reagent for in situ generation of benzonitrile and hydrolyzed as soon as it formed. The catalyst was found to be efficient and can be used for several cycles without loss in activity. Good to excellent yields of primary amides were obtained.

Indole derivative having piperidine ring

The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. It is an object of the present invention to discover an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage, which has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor.