190197-86-5

Basic information

• Product Name: 4-BroMo-3-(broMoMethyl)benzonitrile
• Synonyms: 4-BroMo-3-(broMoMethyl)benzonitrile;BENZONITRILE, 4-BROMO-3-(BROMOMETHYL)-
• CAS NO: 190197-86-5
• Molecular Formula: C₈H₅Br₂N
• Molecular Weight: 274.94
• Mol File: 190197-86-5.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-BroMo-3-(broMoMethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMo-3-(broMoMethyl)benzonitrile(190197-86-5)
• EPA Substance Registry System: 4-BroMo-3-(broMoMethyl)benzonitrile(190197-86-5)

Safety Data

• Hazardous Substances Data: 190197-86-5(Hazardous Substances Data)

Usage

General Description

4-Bromo-3-(bromomethyl)benzonitrile is a chemical compound that belongs to the group of bromomethylbenzonitriles. It is a white solid with a molecular formula of C8H5Br2N and a molar mass of 261.94 g/mol. The compound is mainly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also utilized as an intermediate in the manufacture of dyes and pigments. The presence of bromine atoms in the molecule gives it unique properties, making it a valuable compound in various chemical reactions and processes. However, it is important to handle and store this compound with caution, as brominated chemicals can be hazardous and require proper safety measures.

Upstream product

• 905710-66-9 4-bromo-3-(hydroxymethyl)benzonitrile 
• 845616-12-8 2-bromo-5-cyanobenzoic acid 
• 41963-20-6 4-bromo-3-methylbenzonirtile 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 254744-14-4 2-bromo-5-cyanobenzyl acetate 
• 79008-77-8 2-phenylbenzofuran-5-carbonitrile 
• 128196-01-0 escitalopram 
• 144025-14-9 (+)-Desmethylcitalopram 
• 1352344-90-1 C₂₉H₃₇FN₂O₅ 
• 1352344-85-4 C₁₉H₂₆BNO₄ 
• 1352344-84-3 C₁₃H₁₄BrNO₂ 

Relevant articles and documents

tBuOK-Promoted Cyclization of Imines with Aryl Halides

A transition-metal-free indole synthesis using radical coupling of 2-halotoluenes and imines via the later-stage C-N bond construction was reported for the first time. It includes an aminyl radical generation by C-H cleaving addition of 2-halotoluenes to imines via the carbanion radical relay and an intramolecular coupling of aryl halides with aminyl radicals. One standard condition can be used for all halides including F, Cl, Br, and I. No extra oxidant or transition metal is required.

PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE PREPARATION OF HEPATITIS C VIRUS (HCV) INHIBITORS

The present invention generally relates to a process for preparation of 9-halo-3-(2-haloacetyl)-10,11-dihydro-5H-dibenzo[c,g]chromen-8(9H)-one of Formula I, which is an intermediate in the preparation of Hepatitis C Virus (HCV) inhibitors.

IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

The present disclosure is directed to compounds of formula (Ie) and pharmaceutically acceptable salts thereof, wherein A, B, R1, R2, m, n, X1, X2, X3 and X4 are as defined herein, which are active as inhibitors of S-Nitrosoglutathione reductase (GSNOR). These compounds prevent, inhibit, or suppress the action of GSNOR and are therefore useful in the treatment of GSNOR mediated diseases, disorders, syndromes or conditions such as, e.g., pulmonary hypertension, acute respiratory distress syndrome (ARDS), asthma, bronchospasm, cough, pneumonia, pulmonary fibrosis, interstitial lung diseases, cystic fibrosis and chronic obstructive pulmonary disease (COPD).