19037-34-4

Upstream product

• 567-72-6 cholest-3,5-dien-7-one 
• 567-71-5 5α-cholestan-7-one 
• 3433-23-6 7β-hydroxy-10.13-dimethyl-17β-((R)-1.5-dimethyl-hexyl)-gonene-(5) 
• 555-31-7 aluminum isopropoxide 
• 67-63-0 isopropyl alcohol 
• 74365-07-4 Δ⁸-cholestene 
• 172422-22-9 3β-Chloro-5α-cholestan-7β-ol 
• 141-78-6 ethyl acetate 
• 57-88-5 cholesterol 
• 79732-44-8 cholest-5-en-7-one 
• 604-35-3 Cholesteryl acetate 
• 25904-30-7 5α-cholesten-(8)-one-(7) 
• 15173-50-9 5α-cholest-8-en-3β-ol toluene-p-sulfonate 
• 910-31-6 cholesteryl chloride 

Downstream Products

• 54725-42-7 Δ^8,14-cholestene 
• 40071-65-6 5α-cholest-7-ene 
• 567-71-5 5α-cholestan-7-one 
• 6673-62-7 7β-(toluene-4-sulfonyloxy)-5α-cholestane 

Relevant academic research and scientific papers

A Novel Methylation of Allylic Alcohols Using cis-Dichlorobis(triphenylphosphine)platinum(II)-Tin(II) Chloride Dihydrate Complex Catalyst

The reaction of allylic alcohols in benzene-methanol (3:2) solvent in the presence of cis-dichlorobis(triphenylphosphine)platinum(II)-tin(II) chloride dihydrate complex catalyst afforded allylic methyl ethers.The structure of the obtained compounds was identified by direct comparison with authentic sample.Cholest-4-en-3α-ol, with a quasi-axial hydroxy group, gave a quantitative yield of 3α-methoxycholest-4-ene.On the other hand, cholest-4-en-3β-ol, with a guasi-equatorial hydroxy group, yielded 3β-methoxycholest-4-ene preferentially, but also yielded 3α-methoxycompound as a by-product, lowering the selectivity of the reaction.

Syntheses and CD Studies of New Cholesteno- and -pyrimidines

The syntheses of 5α- and 5β-cholest-3-enopyrimidines (7) and (7') could be achieved by using the hydroxymethylene derivative of cholestan-4-one (5) prepared from cholesterol (1).Their 2'-derivatives 7a-7d and 7'a-7'c were also synthesized. 5α-Cholest-6-enopyrimidine (13) was prepared by the reaction of 5α-cholestan-7-one (12) with tris(formylamino)methane.The CD spectra exhibit at least three Cotton effects between 300 and 210 nm, a first CD band around 290, a second one around 260, and a third one around 220 nm.An earlier developed quadrant rule can be applied to the determination of the sign of the first CD band, while the suggested helicity rule allows prediction of the third CD band. - Keywords: Cholestenopyrimidines / Circular dichroism / Quadrant rule of cholestenopyrimidines

Stereochemical course of hydroboration of highly hindered steroidal olefins. A ready synthesis of 14β- and 8α,14β-steroids

Hydroboration of 5α-cholest-8-ene, 5α,14β-cholest-8-ene and 5α,14β-cholest-7-ene provides a simple route to oxygenated steroids with 14β- and 8α,14β- unnatural stereochemistry.