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190448-57-8

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190448-57-8 Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 190448-57-8 differently. You can refer to the following data:
1. Phase-II metabolite of Ezetimibe, an antihyperlipoproteinemic. A Cholesterol absorption inhibitor. This compound is very hygroscopic. Handle with care
2. Glucuronide metabolite of Ezetimibe
3. Phase-II metabolite of Ezetimibe, an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.This compound is very hygroscopic. Handle with care.

Check Digit Verification of cas no

The CAS Registry Mumber 190448-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,4,4 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 190448-57:
(8*1)+(7*9)+(6*0)+(5*4)+(4*4)+(3*8)+(2*5)+(1*7)=148
148 % 10 = 8
So 190448-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C30H29F2NO9/c31-17-5-1-15(2-6-17)22(34)14-13-21-23(33(28(21)38)19-9-7-18(32)8-10-19)16-3-11-20(12-4-16)41-30-26(37)24(35)25(36)27(42-30)29(39)40/h1-12,21-27,30,34-37H,13-14H2,(H,39,40)/t21-,22+,23-,24?,25-,26?,27?,30+/m1/s1

190448-57-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3S,4S,5R,6S)-6-[4-[(2S,3R)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names Ezetimibe Phenoxy Glucuronide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:190448-57-8 SDS

190448-57-8Downstream Products

190448-57-8Relevant articles and documents

An in vitro assay for evaluation of small-molecule inhibitors of cholesterol absorption

Kvaerno, Lisbet,Ritter, Tobias,Werder, Moritz,Hauser, Helmut,Carreira, Erick M.

, p. 4653 - 4656 (2007/10/03)

Giving cholesterol the brush off: An intestinal brush border membrane vesicle assay has been devised for the convenient in vitro testing of small molecules for inhibition of cholesterol absorption. The assay was used to identify new nonhydrolyzable glycosides as potent cholesterol-absorption inhibitors and an oxazolidinone as an effective replacement of the β-lactam scaffold of ezetimibe (1).

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