190779-61-4

Basic information

• Product Name: 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE
• Synonyms: 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE;Benzene, 2,4-bis(bromomethyl)-1,3,5-triethyl-
• CAS NO: 190779-61-4
• Molecular Formula: C₁₄H₂₀Br₂
• Molecular Weight: 348.1166
• Mol File: 190779-61-4.mol

Chemical Properties

• Boiling Point: 342.5 °C at 760 mmHg
• Flash Point: 187.2 °C
• Appearance: /
• Density: 1.41 g/cm³
• Vapor Pressure: 0.000149mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE(190779-61-4)
• EPA Substance Registry System: 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE(190779-61-4)

Safety Data

• Hazardous Substances Data: 190779-61-4(Hazardous Substances Data)

Usage

Uses

Used in Polymer and Resin Production:
2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE is used as a cross-linking agent for enhancing the properties of polymers and resins. Its reactivity allows for the formation of strong chemical bonds, improving the overall strength, durability, and stability of the resulting materials.
Used in Adhesives Manufacturing:
In the adhesives industry, 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHLBENZENE is used as a key component to improve the bonding strength and resistance of adhesives. Its ability to form robust cross-links contributes to the development of high-performance adhesives suitable for various applications, including automotive, construction, and electronics.
Used in Coatings Industry:
2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE is utilized as a critical ingredient in the formulation of high-performance coatings. Its reactive nature facilitates the creation of durable and weather-resistant coatings, providing excellent protection and longevity to a wide range of surfaces.
Used in Structural Composites:
In the manufacturing of structural composites, 2,4-BIS-(BROMOMETHYL)-1,3,5-TRIETHYLBENZENE is employed as a reactive component to enhance the mechanical properties and chemical resistance of the composite materials. Its incorporation results in lightweight, strong, and durable composites suitable for applications in aerospace, automotive, and construction industries.

InChI:InChI=1/C14H20Br2/c1-4-10-7-11(5-2)14(9-16)12(6-3)13(10)8-15/h7H,4-6,8-9H2,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 102-25-0 1,3,5-triethylbenzene 

Downstream Products

• 360781-68-6 1,3-bis(1-methylimidazole-2-thio)-2,4,6-triethylbenzene 
• 1365994-45-1 C₆H(C₂H₅)3(CH₂NHC₆H₄SH)2 
• 1137672-94-6 1,3-bis-(azidomethyl)-2,4,6-triethylbenzene 
• 1379671-27-8 1-(azidomethyl)-2,4,6,-triethylbenzene 
• 1031684-12-4 1,3-bis[(4,6-dimethylpyridin-2-yl)ainomethyl]2,4,6-triethylbenzene 
• 549507-66-6 di-tert-butyl ((5-(aminomethyl)-2,4,6-triethyl-1,3-phenylene)bis(methylene)) dicarbamate 
• 340722-52-3 1-[[(1,1-dimethylethoxy)carbonyl]aminomethyl]-3,5-bis(aminomethyl)-2,4,6-triethylbenzene 
• 149525-65-5 1,3,5-triethyl-2,4,6-tris(aminomethyl)benzene 
• 190779-62-5 1,3,5-tris(azidomethyl)-2,4,6-triethylbenzene 

Relevant articles and documents

Mechanistic basis of the inhibition of slc11/nramp-mediated metal ion transport by bis-isothiourea substituted compounds

In humans, the divalent metal ion transporter-1 (DMT1) mediates the transport of ferrous iron across the apical membrane of enterocytes. Hence, its inhibition could be beneficial for the treatment of iron overload disorders. Here we characterize the interaction of aromatic bis-isothiourea-substituted compounds with human DMT1 and its prokaryotic homologue EcoDMT. Both transporters are inhibited by a common competitive mechanism with potencies in the low micromolar range. The crystal structure of EcoDMT in complex with a brominated derivative defines the binding of the inhibitor to an extracellular pocket of the transporter in direct contact with residues of the metal ion coordination site, thereby interfering with substrate loading and locking the transporter in its outward-facing state. Mutagenesis and structure-activity relationships further support the observed interaction mode and reveal species-dependent differences between pro-and eukaryotic transporters. Together, our data provide the first detailed mechanistic insight into the pharmacology of SLC11/NRAMP transporters.

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