1908-88-9 Usage
General Description
4,4-dimethylthiazolidine-2-thione is a chemical compound with the molecular formula C6H11NS. It is a sulfur-containing heterocyclic compound with a five-membered ring structure. 4,4-dimethylthiazolidine-2-thione has been found to possess various biological activities, including antibacterial, antifungal, and antioxidant properties. It has been used in the synthesis of pharmaceuticals and as a rubber vulcanization accelerator. Additionally, 4,4-dimethylthiazolidine-2-thione has been investigated for its potential applications in the treatment of diabetes and neurodegenerative diseases. Overall, this compound exhibits a wide range of potential uses in various fields of chemistry and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1908-88-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,0 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1908-88:
(6*1)+(5*9)+(4*0)+(3*8)+(2*8)+(1*8)=99
99 % 10 = 9
So 1908-88-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H9NS2/c1-5(2)3-8-4(7)6-5/h3H2,1-2H3,(H,6,7)
1908-88-9Relevant articles and documents
Thorpe-Ingold effect in the reaction of vicinal amino primary alcohol hydrogen sulfates and carbon disulfide
Chen, Ning,Huang, Zhongyan,Zhou, Chan,Xu, Jiaxi
experimental part, p. 7971 - 7976 (2011/11/14)
The Thorpe-Ingold effect is a key factor that affects the ring-closure rates and efficiency, as well as the structure of products in some ring-closure reactions. The reaction of vicinal amino primary alcohol hydrogen sulfates and carbon disulfide in the presence of potassium hydroxide produces the desired 4,4-disubstituted thiazolidine-2-thiones, and their isomers 5,5-disubstituted derivatives companying with their oxygen analogues 4,4-disubstituted oxazolidine-2-thiones. The formation of 5,5-disubstituted thiazolidine-2-thiones was rationalized via 2,2-disubstituted aziridine-1-carbodithioate intermediates, which were generated due to the Thorpe-Ingold effect. 4,4-Disubstituted oxazolidine-2-thiones were generated from carbon disulfide and free amino alcohols yielded via basic hydrolysis of active amino alcohol hydrogen sulfates in the reaction system.
