190856-75-8

Basic information

• Product Name: bis(2-{(E)-[(4-bromophenyl)imino]methyl}phenolate)copper(II)
• CAS NO: 190856-75-8
• Molecular Weight: 613.795
• Mol File: 190856-75-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: bis(2-{(E)-[(4-bromophenyl)imino]methyl}phenolate)copper(II)(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-{(E)-[(4-bromophenyl)imino]methyl}phenolate)copper(II)(190856-75-8)
• EPA Substance Registry System: bis(2-{(E)-[(4-bromophenyl)imino]methyl}phenolate)copper(II)(190856-75-8)

Safety Data

• Hazardous Substances Data: 190856-75-8(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 106-40-1 4-bromo-aniline 
• 886-34-0 N-salicylidene 4-bromoaniline 
• 6046-93-1 copper(II) acetate monohydrate 
• 886-34-0 4-bromo-N-salicylideneaniline 
• 142-71-2 copper diacetate 
• 14688-83-6 {Cu(C₆H₄(O)CHNC₆H₄(NO₂))2} 

Downstream Products

• 26194-27-4 {Cu(C₆H₄(O)CHNC₆H₅)2} 

Relevant articles and documents

Synthesis and distinct urease enzyme inhibitory activities of metal complexes of Schiff-base ligands: Kinetic and thermodynamic parameters evaluation from TG-DTA analysis

Transition metal [Co, Ni, Cu and Zn(II) acetates] complexes of salicylaldehyde derived Schiff bases, 2-{(E)-[(4-chlorophenyl)imino]methyl} phenol (CIMP) and 2-{(E)-[(4-bromophenyl)imino]methyl}phenol (BIMP) were synthesized and characterized by various analytical and spectroscopic studies. The Schiff base ligands and their metal complexes were also screened for their urease, α-chymotrypsin, acetylcholinesterse and butyrylcholinesterase inhibition activities. The ligands were found active against α-chymotrypsin with IC50 ± S.E.M. = 305.0 ± 3.2 and 330.6 ± 1.6 μM respectively. The copper complexes of both the ligands were found active in inhibiting urease enzyme with IC50 ± S.E.M. = 10.7 ± 0.2 and 5.0 ± 0.1 μM respectively, as compared to standard inhibitor. Structure activity relationship (SAR) was evaluated using autodock programme. It was found that the active complexes block the entrance cavity to the enzyme. All the complexes were evaluated for their thermal degradation studies using TG-DTA analytical methods in static air. Thermodynamic and kinetic parameters were evaluated from the TG/DTA curves using Horowitz-Metzger method.

Bis[N-(4-bromophenyl)salicylaldimine]copper(II)

The compound, bis[2-(4-bromophenyliminomethyl)- phenolato-N,O]copper(II), [Cu(C13H9BrNO)2], has crystallographic inversion symmetry. The Cu11 ion shows a slightly distorted square-planar coordination. The Cu - N and Cu - O distances are 2.019 (4) and 1.879 (4) angstrom, respectively. These distances agree with values in other square-planar coordinated copper(II) complexes.