190954-46-2

Upstream product

• 501-53-1 benzyl chloroformate 
• 190954-45-1 ethyl 1-{(3S,4SR)-4-fluoro-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-44-0 ethyl 1-{(3S,4S)-4-fluoro-1-[(S)-1-phenylethyl]-5-thioxopyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-31-5 ethyl 1-{(3S,4R)-4-fluoro-5-oxo-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-43-9 ethyl 1-{(3S,4S)-4-fluoro-5-oxo-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-59-7 ethyl 1-{(3S)-5-oxo-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 
• 181941-63-9 ethyl 1-{5-oxo-1-[(S)-1-phenylethyl]-2,5-dihydro-1H-pyrrol-3-yl}cyclopropanecarboxylate 
• 181941-61-7 ethyl 3-(1-ethoxycarbonylcyclopropan-1-yl)-3-hydroxybutanoate 
• 181941-62-8 ethyl (E)-3-(1-ethoxycarbonylcyclopropan-1-yl)-2-butenoate 

Downstream Products

• 190954-07-5 5-amino-7-[(3S,4R)-4-(1-aminocycloprop-1-yl)-3-fluoropyrrolidin-1-yl]-6-fluoro-1-[(1R,2S)-2-fluorocycloprop-1-yl]-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid 
• 190954-48-4 (3S,4R)-1-benzyloxycarbonyl-4-[1-(tert-butoxycarbonylamino)cyclopropan-1-yl]-3-fluoropyrrolidine 
• 190954-47-3 1-[(3S,4SR)-1-benzyloxycarbonyl-4-fluoropyrrolidin-3-yl]cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

Synthesis and structure - Activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8- methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents

A series of novel 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolones bearing fluorinated (3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl substituents at the C-7 position (2-4) was synthesized to obtain potent drugs for infections cau