190954-59-7

Upstream product

• 181941-63-9 ethyl 1-{5-oxo-1-[(S)-1-phenylethyl]-2,5-dihydro-1H-pyrrol-3-yl}cyclopropanecarboxylate 
• 181941-61-7 ethyl 3-(1-ethoxycarbonylcyclopropan-1-yl)-3-hydroxybutanoate 
• 181941-62-8 ethyl (E)-3-(1-ethoxycarbonylcyclopropan-1-yl)-2-butenoate 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 190954-07-5 5-amino-7-[(3S,4R)-4-(1-aminocycloprop-1-yl)-3-fluoropyrrolidin-1-yl]-6-fluoro-1-[(1R,2S)-2-fluorocycloprop-1-yl]-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid 
• 190954-07-5 5-amino-7-[(3R,4R)-4-(1-aminocyclopropan-1-yl)-3-fluoropyrrolidin-1-yl]-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-1,4-dihydro-8-methyl-4-oxoquinolin-3-carboxylic acid 
• 190954-36-0 (3R,4R)-1-benzyloxycarbonyl-4-[1-(tert-butoxycarbonylamino)cyclopropan-1-yl]-3-fluoropyrrolidine 
• 190954-48-4 (3S,4R)-1-benzyloxycarbonyl-4-[1-(tert-butoxycarbonylamino)cyclopropan-1-yl]-3-fluoropyrrolidine 
• 181941-59-3 (3R)-1-benzyloxycarbonyl-3-[1-(tert-butoxycarbonylamino)cyclopropan-1-yl]pyrrolidine 
• 190954-34-8 ethyl 1-[(3S,4R)-1-benzyloxycarbonyl-4-fluoropyrrolidin-3-yl]cyclopropanecarboxylate 
• 190954-46-2 ethyl 1-[(3S,4SR)-1-benzyloxycarbonyl-4-fluoropyrrolidin-3-yl]cyclopropanecarboxylate 
• 190954-35-9 1-[(3S,4R)-1-benzyloxycarbonyl-4-fluoropyrrolidin-3-yl]cyclopropanecarboxylic acid 
• 190954-47-3 1-[(3S,4SR)-1-benzyloxycarbonyl-4-fluoropyrrolidin-3-yl]cyclopropanecarboxylic acid 
• 190954-32-6 ethyl 1-{(3S,4R)-4-fluoro-1-[(S)-1-phenylethyl]-5-thioxopyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-44-0 ethyl 1-{(3S,4S)-4-fluoro-1-[(S)-1-phenylethyl]-5-thioxopyrrolidin-3-yl}cyclopropanecarboxylate 
• 190954-43-9 ethyl 1-{(3S,4S)-4-fluoro-5-oxo-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate 
• 503603-90-5 ethyl 1-[(3S)-1-benzyloxycarbonylpyrrolidin-3-yl]cyclopropanecarboxylate 
• 503603-91-6 1-[(3S)-1-benzyloxycarbonylpyrrolidin-3-yl]cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria

A series of novel 6-desfluoro [des-F(6)] and 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methoxyquinolones bearing 3-(1-aminocycloalkyl)pyrrolidin-1-yl substituents at the C-7 position (1-6) was synthesized to obtain potent drugs for nosocomial infect

Synthesis and structure - Activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8- methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents

A series of novel 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolones bearing fluorinated (3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl substituents at the C-7 position (2-4) was synthesized to obtain potent drugs for infections cau

DEHALOGENO COMPOUNDS

3-(1-Aminocycloalkyl)pyrrolidinyl-substituted-6-dehalodeno(hydrogen-substituted)quinolon carboxylic acid derivatives having specific substitunets as represented by the following formula (I), its salts, and hydrates thereof exhibit a broad and potent antibacterial activity on gram-negative and gram-positive bacteria, in particular, resistant bacteria typified by gram-positive cocci, including MRSA, PRSP and VRE . Thus these compounds are usable as drugs.