19096-31-2

Upstream product

• 140389-06-6 2,3-dihydro-2-phenyl-1H-inden-1-ol 
• 55165-45-2 2-cyano-benzenediazonium tetrafluoroborate 
• 536-74-3 phenylacetylene 
• 63488-21-1 2-(diphenylmethyl)-2,3-dihydro-2-phenyl-1H-indene-1,3-dione 
• 140409-82-1 cis,trans-2-(diphenylmethyl)-2,3-dihydro-2-phenyl-1H-indene-1,3-diol 
• 21375-88-2 1-bromo-2-(phenylethenyl)benzene 
• 52711-23-6 3-(methylthio)-2-phenyl-1H-inden-1-one 
• 501-65-5 diphenyl acetylene 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 

Downstream Products

• 16619-12-8 2-phenyl-indan-1-one 

Relevant academic research and scientific papers

Nove [3 + 2] radical annulations of cyano-substituted aryl radicals with alkynes

New radical annulation reactions are described involving addition of ortho-cyano-substituted aryl radicals to alkynes. Addition of the aryl radical to the C-C triple bond gives rise to a vinyl radical, whose cyclisation onto the carbon atom of the nitrile

Preparation method of indanone derivatives

The invention relates to a synthesis method of organic compounds. In order to solve the problems of more reaction steps, more raw material variety and long reaction time in the current indanone derivative synthesis and relatively high catalyst price in some methods, the invention provides a preparation method of indanone and derivatives thereof. The indanone derivatives are prepared by reacting o-alkynylbenzaldehyde serving as an initial material with a catalyst, an oxidant and a solvent at 25-100 DEG C for 1-24h. The synthesis method is convenient to realize aftertreatment, simple and convenient to operate, incapable of producing waste acid in reaction, environment-friendly and capable of realizing a reaction under a relatively mild condition. The synthesis method is a novel route for synthesizing the indanone derivatives.

MeOTf-Induced Carboannulation of Isothiocyanates and Aryl Alkynes with C=S Bond Cleavage: Access to Indenones

MeOTf-induced carboannulation of alkyl isothiocyanates and aryl alkynes for the synthesis of indenones in good yields under metal-free conditions with C=S bond cleavage is described. The thioalkoxy group at the 3-position of the indenone can also be converted into other functional groups, such as phenyl, methylsulfonyl, amino, and ethoxy groups.

An indenone synthesis involving a new aminotransfer reaction and its application to dibenzopentalene synthesis

o-(Phenylethynyl)phenyllithiums, generated by treatment of o-(phenylethynyl)bromobenzenes with tBuLi, were quenched with N,N-dimethylcarboamides to afford various 2-phenylindenone derivatives in moderate to good yields upon acidic workup. The choice of lithiation reagents was critical. When n-butyllithium was used the yields were reduced. The N-alkyl groups in the carboamides were also important: quenching with N,N-diethylbenzamides also afforded 2,3-diphenylindenones as the sole isolated products, but quenching with N-benzoylpiperidine led to 2-benzoyltolane in good yield. Control experiments revealed that the reactions proceed through a multi-step reaction sequence involving a novel intramolecular transamination to the α-acetylenic carbon of the alkynyl group. The method was applicable to the synthesis of dibenzopentalene derivatives as well as various indenone derivatives. A mechanism for the reaction is discussed.

Synthesis of Tribenzotriquinacene and Some centro-Substituted Derivatives

The syntheses of tribenzotriquinacene (1a) and five centro-substituted derivatives, 1b-1e and 1g, as well as of the related diindan 13 are reported.The three-step synthetic sequences include the reduction of suitably substituted 2-benzhydryl-1,3-indandion