190974-25-5

Upstream product

• 64370-42-9 allyl 2-oxoacetate 
• 135297-16-4 (3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-((R)-2-oxo-cyclohexyl)-azetidin-2-one 

Downstream Products

• 190974-40-4 [(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-((1R,3S)-3-hydroxymethyl-2-oxo-cyclohexyl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 190974-26-6 [(3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-oxo-4-((R)-2-oxo-cyclohexyl)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 

Relevant academic research and scientific papers

The stereoselective synthesis of 4-formyltrinem, a key intermediate for novel trinems

The stereoselective synthesis of a protected 4-formyltrinem 8 was accomplished in good yield. This compound is a potential intermediate in the synthesis of a wide range of 4-alkyl and alkenyl substituted trinem antibiotics, as evidenced by its reaction with a series of phosphoranes and phosphonates.