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2,4-Hexadienoic acid, 6-bromo-, methyl ester, (E,E)is a chemical compound characterized by the molecular formula C8H11BrO2. It represents the methyl ester form of 6-bromo-2,4-hexadienoic acid, featuring double bonds in the E,E configuration. 2,4-Hexadienoic acid, 6-bromo-, methyl ester, (E,E)is utilized in a range of chemical and pharmaceutical applications, primarily as a building block in the synthesis of organic compounds. Its potential biological activity also makes it a promising candidate for the development of new drugs and pharmaceuticals. However, due to its potential hazardous or irritating effects on human health and the environment, careful handling is advised.

51010-88-9

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51010-88-9 Usage

Uses

Used in Chemical Synthesis:
2,4-Hexadienoic acid, 6-bromo-, methyl ester, (E,E)is used as a building block in the chemical synthesis of various organic compounds. Its unique structure with double bonds and a bromine atom allows for versatile reactions and the creation of a wide array of chemical products.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,4-Hexadienoic acid, 6-bromo-, methyl ester, (E,E)is used as a precursor in the development of new drugs and pharmaceuticals. Its potential biological activity and chemical properties make it a valuable component in the synthesis of medicinal compounds, contributing to the advancement of novel therapeutic agents.
Used in Research and Development:
2,4-Hexadienoic acid, 6-bromo-, methyl ester, (E,E)is also utilized in research and development settings to explore its chemical properties, reactivity, and potential applications in various fields. This includes studying its interactions with other compounds and understanding its role in chemical reactions, which can lead to the discovery of new applications and uses.

Check Digit Verification of cas no

The CAS Registry Mumber 51010-88-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,0,1 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 51010-88:
(7*5)+(6*1)+(5*0)+(4*1)+(3*0)+(2*8)+(1*8)=69
69 % 10 = 9
So 51010-88-9 is a valid CAS Registry Number.

51010-88-9Relevant articles and documents

A DNA-Encoded Chemical Library Incorporating Elements of Natural Macrocycles

Stress, Cedric J.,Sauter, Basilius,Schneider, Lukas A.,Sharpe, Timothy,Gillingham, Dennis

supporting information, p. 9570 - 9574 (2019/06/24)

Here we show a seven-step chemical synthesis of a DNA-encoded macrocycle library (DEML) on DNA. Inspired by polyketide and mixed peptide-polyketide natural products, the library was designed to incorporate rich backbone diversity. Achieving this diversity, however, comes at the cost of the custom synthesis of bifunctional building block libraries. This study outlines the importance of careful retrosynthetic design in DNA-encoded libraries, while revealing areas where new DNA synthetic methods are needed.

A novel catalytic asymmetric route towards skipped dienes with a methyl-substituted central stereogenic carbon

Huang, Yange,Fananas-Mastral, Martin,Minnaard, Adriaan J.,Feringa, Ben L.

, p. 3309 - 3311 (2013/06/04)

A highly efficient method for the enantioselective synthesis of 1,4-dienes (skipped dienes) with a methyl-substituted central stereogenic carbon using copper-catalysed asymmetric allylic alkylation of diene bromides was developed. Excellent regio- and enantioselectivity (up to 97 : 3 SN2′/ SN2 ratio and 99% ee) were achieved with broad substrate scope. The Royal Society of Chemistry 2013.

Extending the stetter reaction with 1,6-acceptors

Law, Katherine R.,McErlean, Christopher S. P.

, p. 15852 - 15855 (2014/04/03)

Pace Stetter: A new N-heterocyclic carbene (NHC)-catalysed transformation is described-the intramolecular vinylogous Stetter reaction. This transformation can be effected with both thiazolium and triazolium-based catalysts, using aromatic and aliphatic aldehydes, employing α,β,γ,δ- unsaturated esters, ketones, phosphonates and N-acylpyrroles, and can be conducted enantioselectively (see scheme). Copyright

Ruthenium-catalyzed regio- and enantioselective allylic substitution with water: Direct synthesis of chiral allylic alcohols

Kanbayashi, Naoya,Onitsuka, Kiyotaka

supporting information; experimental part, p. 5197 - 5199 (2011/06/26)

Less is more: A new route to access chiral allylic alcohols through the regio- and enantioselective substitution of monosubstituted allylic chlorides with water has been developed. The reaction is catalyzed effectively by planar-chiral cyclopentadienyl ruthenium complexes (see scheme). Copyright

Syntheses of structurally diverse amino acids, including δ-hydroxylysine, using the acyl nitroso Diels-Alder reaction

Bollans, Lee,Bacsa, John,O'Farrell, Daniel A.,Waterson, Scott,Stachulski, Andrew V.

supporting information; experimental part, p. 2160 - 2163 (2010/06/14)

By virtue of its ability to introduce amino and hydroxy functionalities in a 1,4-relationship with fully controlled relative stereochemistry, the acyl nitroso Diels-Alder (ANDA) reaction is ideally suited to the synthesis of structurally diverse, includin

Synthesis of two bioactive natural products: FR252921 and pseudotrienk acid B

Amans, Dominique,Bellosta, Veronique,Cossy, Janine

experimental part, p. 3457 - 3473 (2009/12/26)

Concise and highly convergent syntheses of the immunosuppressive agent FR252921 and the related antimicrobial natural product pseudotrienic acid B were achieved from a common intermediate by using optically active titanium complexes to control the configuration of the stereogenic centers, a highly stereoand regioselective cross-metathesis to generate the triene moieties, and a Stille cross-coupling to install the dienic units.

Developing an asymmetric, stereodivergent route to selected 6-deoxy-6-fluoro-hexoses

Caravano, Audrey,Field, Robert A.,Percy, Jonathan M.,Rinaudo, Giuseppe,Roig, Ricard,Singh, Kuldip

experimental part, p. 996 - 1008 (2009/05/30)

Free radical bromination and nucleophilic fluorination allows the conversion of methyl sorbate into the 6-fluoro analogue which undergoes sequential asymmetric dihydroxylation reactions. A range of 6-deoxy-6- fluorosugars were prepared by using different

HISTONE DEACETYLASE INHIBITORS

-

, (2008/06/13)

The present invention provides histone deacetylase inhibitors of general formula (I), process for the preparation of such compounds and uses of the compounds in medicine.

Synhtesis of Some Aromatic Prostaglandin Analogues. Part 1

Durrant, Graham,Green, Richard H.,Lambeth, Paul F.,Lester, Michael G.,Taylor, Nigel R.

, p. 2211 - 2214 (2007/10/02)

7-heptanoic acid (4) has been prepared in six steps from 3,5-dimethoxybenzaldehyde.

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