19102-90-0

Basic information

• Product Name: DIMETHYL HEXADECANEDIOATE
• Synonyms: DIMETHYL-1,16-HEXADECANEDIOATE;DIMETHYL HEXADECANEDIOATE;1,14-Tetradecanedicarboxylic acid dimethyl ester;Dimethyl thapsate;Hexadecadioic acid, dimethyl ester;hexadecanedioic acid,dimethyl ester
• CAS NO: 19102-90-0
• Molecular Formula: C₁₈H₃₄O₄
• Molecular Weight: 314.46
• Mol File: 19102-90-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 53 °C
• Boiling Point: 172 °C / 1mmHg
• Flash Point: 157.5 °C
• Appearance: /
• Density: 0.945 g/cm³
• CAS DataBase Reference: DIMETHYL HEXADECANEDIOATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL HEXADECANEDIOATE(19102-90-0)
• EPA Substance Registry System: DIMETHYL HEXADECANEDIOATE(19102-90-0)

Safety Data

• Hazardous Substances Data: 19102-90-0(Hazardous Substances Data)

Usage

General Description

DIMETHYL HEXADECANEDIOATE, also known as dimethyl palmitate, is a chemical compound with the molecular formula C18H34O4. It is a colorless to pale yellow liquid with a faint odor and is insoluble in water. This chemical is commonly used as a fragrance ingredient in cosmetics, skin care products, and perfumes due to its fruity and floral scent profile. It is also utilized as a flavoring agent in food and beverages. Additionally, dimethyl hexadecanedioate has applications in the formulation of personal care products and as a solvent in various industrial processes. It is important to handle and use this compound with caution, as it can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C18H34O4/c1-21-17(19)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(20)22-2/h3-16H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 505-54-4 thapsic acid 
• 112-62-9 Methyl oleate 
• 112-82-3 hexadecanyl bromide 
• 186581-53-3 diazomethane 
• 2104-19-0 azelaic monomethyl ester 
• 16355-92-3 1,10-diiododecane 
• 292638-85-8 acrylic acid methyl ester 
• 21094-94-0 17-Phenylstearinsaeure-methylester 
• 1732-10-1 Dimethyl azelate 
• 1593-55-1 azelaic acid monoethyl ester 
• 5399-02-0 heptadecanenitrile 
• 6938-66-5 1-Bromodocosane 
• 4276-49-7 1-Bromoeicosane 

Downstream Products

• 18451-85-9 15-(methoxycarbonyl)pentadecanoic acid 
• 956-82-1 3-methylcyclopentadecanone 
• 929-77-1 behenic acid methyl ester 
• 661-19-8 1-docosanol 
• 505-54-4 thapsic acid 
• 7735-42-4 1,16-hexadecanediol 
• 502-72-7 cyclopentadecanone 

Relevant articles and documents

Two-directional synthesis of (+)-ancepsenolide

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Six New Polyacetylenic Alcohols from the Marine Sponges Petrosia sp. and Halichondria sp.

Six new polyacetylenic alcohols, termed strongylotriols A and B; pellynols J, K, and L; and isopellynol A, together with three known polyacetylenic alcohols, pellynols A, B, and C were isolated from the marine sponges Petrosia sp., and Halichondria sp. collected in Okinawa, Japan. Their planer structures were determined based on 2D-NMR and mass spectrometric analysis of the degraded products by RuCl3 oxidation. The absolute stereochemistry of isolates was examined by their Mosher's esters. The strongylotriols were found to be optically pure compounds, whereas the pellynols are diastereomeric mixtures at the C-6 position. Proliferation experiments using the HeLa and K562 cell lines suggested that the essential structural units for activity are the "hexa-2,4-diyn-1,6-diol" and "pent-1-en-4-yn-3-ol" on the termini.

A facile synthesis of long chain acyclic alkanols via Kolbe coupling: 1-Docosanol and 1-triacontanol

A convenient synthesis of long chain acyclic alkanols viz., 1-docosanol and 1-triacontanol has been devised via Kolbe radical coupling of mono-methyl azelate 2, which has been synthesized from azelaic acid 1. The dimer viz. dimethyl thapsate 3, on Ba(OH)2 hydrolysis affords mono-methyl thapsate 4, which upon mixed Kolbe coupling with appropriate alkanoic acid [CH3(CH)2)nCOOH, n = 6 for 1-docosanol and n = 14 for 1-tri-acontanol] gives the cross coupled products methyl docosanoate 7 and methyl triacontanoate 8 along with the radical dimers dimethyl triacontanedioate 4′ and tetradecane 5′/triacontane 6′ as byproducts. Compounds 7 and 8 on LAH reduction in dry THF yield 1-docosanol 9 and 1- triacontanol 10, respectively in high yields. The mixed anodic coupling has been studied by varying parameters viz. degree of neutralization and molar ratio of compounds 4 and C8/C16 alkanoic acid, current density, anode material etc.