191024-62-1

Upstream product

• 68366-59-6 (2R,4aR,6S,7R,8aR)-6-methoxy-8-oxo-2-phenyl-7-phenylcarbonyloxyperhydropyrano[3,2-d][1,3]dioxine 
• 75-61-6 dibromodifluoromethane 
• 28642-64-0 methyl 2-O-benzoyl-4,6-di-O-benzylidene-α-D-glucopyranoside 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 

Downstream Products

• 191024-63-2 Benzoic acid (2R,4aR,6S,7R,8R,8aS)-8-difluoromethyl-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 
• 191024-65-4 (2R,4aR,6S,7R,8aS)-8-[1-Fluoro-meth-(Z)-ylidene]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 191024-67-6 (2R,4aR,6S,8aS)-6-Methoxy-2-phenyl-8-trifluoromethyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine 
• 205688-37-5 Benzoic acid (2S,3R,6S)-6-hydroxymethyl-2-methoxy-4-trifluoromethyl-3,6-dihydro-2H-pyran-3-yl ester 
• 191024-68-7 Benzoic acid (2S,3R,6S)-2-methoxy-4-trifluoromethyl-6-trityloxymethyl-3,6-dihydro-2H-pyran-3-yl ester 

Relevant academic research and scientific papers

Highly stereoselective route to aldol products incorporating fluorine containing methyl groups starting from a single D-glucose-derived intermediate

Chiral aldol structures with fluorine modifications on a methyl group have been realized by utilization of the relatively rigid cyclic intermediates from the very common chiral pool compound, D-glucose, leading to attainment of the high diastereoselectivi