Highly stereoselective route to aldol products incorporating fluorine containing methyl groups starting from a single D-glucose-derived intermediate

Article abstract of DOI:10.1016/S0957-4166(97)00120-1

Chiral aldol structures with fluorine modifications on a methyl group have been realized by utilization of the relatively rigid cyclic intermediates from the very common chiral pool compound, D-glucose, leading to attainment of the high diastereoselectivi