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191043-81-9

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191043-81-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 191043-81-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,0,4 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 191043-81:
(8*1)+(7*9)+(6*1)+(5*0)+(4*4)+(3*3)+(2*8)+(1*1)=119
119 % 10 = 9
So 191043-81-9 is a valid CAS Registry Number.

191043-81-9Relevant articles and documents

INHIBITORS OF JANUS KINASES

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Page/Page column 59, (2010/04/03)

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2). The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 and TYK2 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer

SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION

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Page/Page column 322, (2008/12/05)

The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.

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