191089-59-5

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Basic information

Product Name: K-7174
Synonyms: K-7174
CAS NO:191089-59-5
Molecular Formula: C₃₃H₄₈N₂O₆
Molecular Weight: 568.74402
EINECS: N/A
Product Categories: N/A
Mol File: 191089-59-5.mol
Article Data: 2

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: 2-8°C
Solubility: N/A
CAS DataBase Reference: K-7174(CAS DataBase Reference)
NIST Chemistry Reference: K-7174(191089-59-5)
EPA Substance Registry System: K-7174(191089-59-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 191089-59-5(Hazardous Substances Data)

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K-7174(FREEBASE)
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Xiamen Jenny Chemical Technology Co., Ltd.
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K-7174 cas 191089-59-5
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BOC Sciences
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K-7174(FREE BASE) CAS No.191089-59-5
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Guangdong Juda Chemical Industrial Co.,Limited
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1H-1,4-Diazepine, hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-pentenyl]-
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SAGECHEM LIMITED
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K-7174
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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K-7174with factory price
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Wuhan Sun-shine Bio-technology Corporation Limited
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191089-59-5 Usage

General Description

K-7174 is a synthetic chemical compound, specifically a potent and selective inhibitor of the enzyme farnesyl protein transferase (FPTase). FPTase is responsible for adding a farnesyl group to proteins, which can play a role in the development of certain types of cancer. K-7174 has been studied for its potential use as an anti-cancer agent, as inhibiting FPTase can prevent the activation of certain proteins involved in cancer growth and progression. Research has shown that K-7174 may be effective in suppressing tumor growth in animal models, making it a promising candidate for further development as a cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 191089-59-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,0,8 and 9 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 191089-59:
(8*1)+(7*9)+(6*1)+(5*0)+(4*8)+(3*9)+(2*5)+(1*9)=155
155 % 10 = 5
So 191089-59-5 is a valid CAS Registry Number.

191089-59-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-enyl)-1,4-diazepane

1.2 Other means of identification

Product number	-
Other names	N,N'-bis-((E)-5-(3,4,5-trimethoxyphenyl)-4-pentenyl)homopiperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:191089-59-5 SDS

191089-59-5Upstream product

191089-59-5Downstream Products

191089-60-8 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-enyl)-1,4-diazepane dihydrochloride

191089-59-5Related news

Suppression of cytokine response by GATA inhibitor K-7174 (cas 191089-59-5) via unfolded protein response07/16/2019

K-7174, a GATA-specific inhibitor, is a putative anti-inflammatory agent that attenuates effects of inflammatory cytokines in certain cell types. However, molecular mechanisms involved have not been elucidated. We found that, in glomerular podocytes, induction of monocyte chemoattractant protein...detailed

191089-59-5Relevant articles and documents

A straightforward synthesis of K-7174, a GATA-specific inhibitor

Majik, Mahesh S.,Yu, Jin Ha,Jeong, Lak Shin

, p. 2903 - 2906 (2012/10/29)

K-7174, a GATA-specific inhibitor, is a putative anti-inflammatory agent that attenuates effects of inflammatory cytokines in certain cell types. An expeditious four-step synthesis of K-7174 is described in this paper. The route employs Wittig olefination

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