191089-60-8 Usage
Uses
Used in Pharmaceutical Industry:
K-7174, 1,4-Bis[5-(3,4,5-triMethoxyphenyl)-4(E)-pentenyl]hexahydro-1H-1,4-diazepine is used as an anti-inflammatory agent for its ability to attenuate the effects of inflammatory cytokines in specific cell types. This application is particularly relevant in the development of treatments for various inflammation-related conditions, as it may help to reduce the severity and progression of these diseases.
Used in Research Applications:
In the field of research, K-7174, 1,4-Bis[5-(3,4,5-triMethoxyphenyl)-4(E)-pentenyl]hexahydro-1H-1,4-diazepine serves as a valuable tool for studying the role of GATA transcription factors in cellular processes. By inhibiting GATA, researchers can gain insights into the molecular mechanisms underlying inflammation and other related conditions, potentially leading to the discovery of novel therapeutic targets and strategies.
Used in Drug Development:
K-7174, 1,4-Bis[5-(3,4,5-triMethoxyphenyl)-4(E)-pentenyl]hexahydro-1H-1,4-diazepine is used as a lead compound in the development of new anti-inflammatory drugs. Its GATA-specific inhibitory activity makes it a promising candidate for further optimization and refinement, with the goal of creating more potent and selective inhibitors that can be used to treat a range of inflammation-related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 191089-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,0,8 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 191089-60:
(8*1)+(7*9)+(6*1)+(5*0)+(4*8)+(3*9)+(2*6)+(1*0)=148
148 % 10 = 8
So 191089-60-8 is a valid CAS Registry Number.
191089-60-8Relevant academic research and scientific papers
A straightforward synthesis of K-7174, a GATA-specific inhibitor
Majik, Mahesh S.,Yu, Jin Ha,Jeong, Lak Shin
, p. 2903 - 2906 (2012/10/29)
K-7174, a GATA-specific inhibitor, is a putative anti-inflammatory agent that attenuates effects of inflammatory cytokines in certain cell types. An expeditious four-step synthesis of K-7174 is described in this paper. The route employs Wittig olefination
