1911-74-6 Usage
Uses
Used in Organic Synthesis:
Trityl-L-Proline is used as a protecting group for the carboxylic acid functional group, allowing selective reactions to occur without interference from the carboxylic acid moiety. This selective protection is crucial for the synthesis of complex organic compounds, ensuring the integrity and reactivity of the desired functional groups.
Used in Pharmaceutical Production:
In the pharmaceutical industry, Trityl-L-Proline is utilized as a key intermediate in the synthesis of various drugs. Its ability to protect the carboxylic acid group during the assembly of complex molecular structures contributes to the successful production of a wide range of pharmaceuticals.
Used in Agrochemical Production:
Trityl-L-Proline also plays a significant role in the agrochemical industry, where it is employed in the synthesis of various agrochemicals. Its protective properties ensure the successful synthesis of active ingredients in pesticides, herbicides, and other agricultural chemicals.
Used in Peptide Synthesis:
In the field of peptide synthesis, Trityl-L-Proline is used as a protecting agent for the carboxyl group of proline during the assembly of peptide chains. This protection is essential for the successful formation of peptide bonds and the synthesis of biologically active peptides and proteins.
Overall, Trityl-L-Proline is a vital component in the development and production of a diverse array of organic compounds, playing a critical role in various industries, including pharmaceuticals, agrochemicals, and peptide synthesis. Its protective properties and versatility make it an indispensable reagent in modern organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1911-74-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,1 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1911-74:
(6*1)+(5*9)+(4*1)+(3*1)+(2*7)+(1*4)=76
76 % 10 = 6
So 1911-74-6 is a valid CAS Registry Number.
1911-74-6Relevant academic research and scientific papers
TRITYLATION REACTIONS BASED ON METALLIC CATALYSIS
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Page/Page column 22-23, (2010/11/25)
The invention relates to a method for preparing tritylated compounds in which protic functional groups are protected with the triphenylmethyl group, method based on the homogeneous catalysis exercised by salts or metal complexes in organic solvents. The invention relates in particular to a method for the selective tritylation of some groups, obtained both directly and by selective detritylation, with methods based on metallic catalysis. The application to amino acids, typical substrates not suitable to be subjected as such to homogeneous tritylations in organic solvents, indicates the ability of the method to extend also to hydrophilic substrates. The method allows to obtain with high yield pertrityl amino acids, N-tritylamino acids or amino acids tritylated only in lateral chain, compounds which heretofore were either difficult to obtain in aqueous solvents or obtainable through indirect methods. All, in any case, are important intermediates in peptide synthesis.
Efficient "One-Pot" Synthesis of N-Trityl Amino Acids
Barlos, Kleomenis,Papaioannou, Dionysios,Theodoropoulos, Dimitrios
, p. 1324 - 1326 (2007/10/02)
A sequential procedure has been developed whereby neutral amino acids 1 were tritylated via their corresponding trimethylsilyl esters 2 to afford, after mild hydrolysis, N-trityl amino acids 3 in high yields and purity.Hydroxy amino acids 4 were preferent
