191277-30-2Relevant articles and documents
Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M
Dallanoce, Clelia,Conti, Paola,De Amici, Marco,De Micheli, Carlo,Barocelli, Elisabetta,Chiavarini, Milena,Ballabeni, Vigilio,Bertoni, Simona,Impicciatore, Mariannina
, p. 1539 - 1547 (1999)
Two subseries of nonquaternized (5a-10a) and quaternized derivatives (5b-10b) related to oxotremorine and oxotremorine-M were synthesized and tested. The agonist potency at the muscarinic receptor subtypes of the new compounds was estimated in three class
Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine
Conti, Paola,Dallanoce, Clelia,De Amici, Marco,De Micheli, Carlo,Ebert, Bjarke
, p. 1033 - 1036 (2007/10/03)
The synthesis and radioligand binding assays of a group of muscarinic ligands related to oxotremorine are reported. The new compounds displayed binding affinities comparable to those of the parent molecule with the exception of the trimethylammonium salt
