19139-76-5Relevant academic research and scientific papers
Convergent and stereoselective synthesis of (-)-zeaenol
Kumar, Rayala Naveen,Meshram
, p. 5669 - 5677 (2015)
Stereoselective synthesis of (-)-zeaenol has been accomplished from d-xylose as a chiral pool starting material. The key steps of this convergent synthetic strategy involves a Stille coupling, a Noyori reduction, a Julia-Kocienski olefination and a macrolactonization to obtain (-)-zeaenol. We have also explored a Sonogashira coupling along with a Trost protocol for the intramolecular hydrosilylation on the homopropargylic alcohol system as an alternative synthetic approach to this molecule.
