191410-01-2

Upstream product

• 6485-40-1 (R)-Carvone 
• 158252-77-8 (2R,3R,5R)-3-hydroxy-2-methyl-5-(1-methylethenyl)cyclohexanone 
• 36616-60-1 (1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one 
• 191410-00-1 (2R,3R,5R)-3-tert-butyldimethylsilyloxy-2-methyl-5-(1-methylethenyl)cyclohexanone 

Downstream Products

• 202859-90-3 (3R,5R,6R)-5,6-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(tert-butyl-methoxy-phenyl-silanyloxy)-heptanoic acid methoxy-methyl-amide 
• 202859-91-4 (3R,5R,6R)-5-(tert-Butyl-dimethyl-silanyloxy)-3-(tert-butyl-methoxy-phenyl-silanyloxy)-6-hydroxy-heptanoic acid methoxy-methyl-amide 
• 202859-87-8 (4R,6R,7R)-6-(tert-Butyl-dimethyl-silanyloxy)-4-(tert-butyl-methoxy-phenyl-silanyloxy)-7-methyl-oxepan-2-one 

Relevant academic research and scientific papers

Bryostatin: A novel asymmetric synthesis of the C27-C34 fragment starting from (R)-carvone as chiral template

(R)-Carvone is a suitable chiral template for the synthesis of differently protected (4S,6R,7R)-trihydroxy-1-octyne derivatives, the C27-C34 fragment of bryostatins. Also other potentially interesting chiral building blocks are described.

(R)-Carvone as chiral template for the synthesis of some polyols

Some (4S,6R,7R) 4,6,7-trihydroxyheptyl derived building blocks have been obtained from (R)-carvone as the chiral template.A key-step is the Baeyer-Villiger oxidation of a suitable intermediate.