191478-99-6

Usage

Uses

Used in Pharmaceutical Industry:
Benzoic acid, 4-amino-2,6-difluoro-, methyl ester (9CI) is used as an intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique chemical structure, including the presence of an amino group and two fluorine atoms, may contribute to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, Benzoic acid, 4-amino-2,6-difluoro-, methyl ester (9CI) is used as an intermediate in the synthesis of agrochemicals. Its properties may be leveraged to develop new pesticides or other agricultural chemicals that can improve crop protection and yield.
Used in Chemical Research:
Benzoic acid, 4-amino-2,6-difluoro-, methyl ester (9CI) is also utilized in chemical research for studying the properties and reactions of benzoic acid derivatives. This can lead to a better understanding of the structure-activity relationships and potential applications of related compounds in various fields.

Upstream product

• 67-56-1 methanol 
• 28314-80-9 2,4,6-trifluorobenzoic acid 
• 773134-11-5 4-bromo-2,6-difluorobenzoic acid methyl ester 
• 1329166-92-8 4-(benzhydrylidene-amino)-2,6-difluoro-benzoic acid methyl ester 
• 129589-63-5 methyl 4-((tert-butyloxycarbonyl)amino)-2,6-difluorobenzoate 
• 183065-68-1 4-bromo-2,6-difluorobenzoic acid 

Relevant academic research and scientific papers

Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

SUBSTITUTED OXOPYRIDINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CARDIOVASCULAR DISORDERS

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF

Provided are sulfonamide derivatives of a specific chemical structure in which a sulfonamide group having, as a substituent, a phenyl group or a heterocyclic group having a hetero atom(s) as a constituent element(s) is present at its terminal, and pharmaceutically acceptable salts thereof. These compounds are novel compounds having excellent α4 integrin-inhibitory action.

Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thichroman and 1,2,3,4-tetrahydroquinolinecarboxlic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity

Compounds of the formula wherein the symbols have the meaning defined in the specification have retinoid-like biological activity.

Methods of treatment with compounds having RARα receptor specific or selective activity

Retinoid compounds which act specifically or selectively on RARα receptor subtypes in preference over RARβ and RARγ receptor subtypes, posses desirable pharmaceutical properties associated with retinoids, and are particularly suitable for treatment of tumors, such as acute monocytic leukemia, cervical carcinoma, myeloma, ovarian carcinomas and head and neck carcinomas, without having one or more undesirable side effects of retinoids, such as inducement of weight loss, mucocutaneous toxicity, skin irritation and teratogenecity.

Substituted heteroarylamides having retinoid-like biological activity

Compounds of the formula STR1 wherein the symbols have the meaning described in the specification, have retinoid-like biological activity.

Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity

Compounds of the formula STR1 where the symbols have the meaning defined in the specification have retinoid-like biological activity.