773134-11-5Relevant articles and documents
Single-Crystalline UiO-67-Type Porous Network Stable to Boiling Water, Solvent Loss, and Oxidation
Wong, Yan-Lung,Yee, Ka-Kit,Hou, Yun-Long,Li, Jiaqian,Wang, Zuankai,Zeller, Matthias,Hunter, Allen D.,Xu, Zhengtao
, p. 6198 - 6201 (2018)
With methylthio groups flanking the carboxyl groups, the 3,3′,5,5′-tetrakis(methylthio)biphenyl dicarboxylate (TMBPD) linker forms a zirconium(IV) carboxylate porous framework featuring the topology of the UiO-67 prototype, i.e., with a face-centered-cubic array of the Zr6O4(OH)4 clusters. Thioether functionalization proves valuable because the ZrTMBPD crystal is found to be exceptionally stable not only upon long-term exposure to air but also in boiling water and a broad range of pH conditions. The hydrophobicity of the metal-organic framework can also be tuned by simple H2O2 oxidation, as illustrated in the water contact-angle measurement of the pristine and H2O2-treated ZrTMBPD solid.
HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS
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Paragraph 234, (2018/03/25)
The invention relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): (I), wherein L1, A, X1, X2, R1, R2, and R3 are described herein.
INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
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Page/Page column 28, (2017/09/28)
The invention relates to a compound of Formula (I), or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of indoleamine 2,3-dioxygenase. The inventi