191479-39-7

Upstream product

• 141248-89-7 2-hydroxymethyl-2-phenyloxirane 
• 87234-28-4 1,3-dichloro-2-hydroxy-2-phenylpropane 
• 1005-91-0 2-phenyl-2-(chloromethyl)oxirane 
• 591-51-5 phenyllithium 

Downstream Products

• 152774-05-5 (S)-(2-phenyloxiran-2-yl)methanol 
• 191479-65-9 (R)-2-Methoxymethyl-2-phenyl-oxirane 
• 2406-22-6 (2S)-2-phenylpropane-1,2-diol 
• 141248-89-7 2-hydroxymethyl-2-phenyloxirane 
• 191479-78-4 (S)-3-chloro-2-phenylpropane-1,2-diol 
• 191479-91-1 Acetic acid (R)-3-chloro-2-hydroxy-2-phenyl-propyl ester 

Relevant academic research and scientific papers

Tungsten-, molybdenum-, and cerium-promoted regioselective and stereospecific halogenation of 2,3-epoxy alcohols and 2,3-epoxy sulfonamides

The first catalytic regioselective and stereospecific halogenation of 2,3-epoxy alcohols and 2,3-epoxy sulfonamides has been developed. Under the catalysis of commercially available W- or Mo-salts, complemented by the method using cerium halides, the C-3

An improved method for the addition reactions of 1,3-dichloroacetone with combined organolithium-cerium trichloride reagents

Alkyl-, phenyl- and alkynyllithium reagents in combination with anhydrous cerium(III) chloride underwent addition reactions with 1,3-dichloroacetone in a very efficient manner. The addition products are versatile precursors for 2-substituted epichlorohydrins and glycidols. Fluconazole, a potent antifungal agent, was thus synthesized in 67% yield by addition of 1,3-dichloroacetone to 2,4-difluorophenyllithium in the presence of cerium(III) chloride, followed by substitution of the chlorine atoms with 1,2,4-triazole.