1916-04-7

Basic information

• Product Name: Benzoic acid, 2-(4-methoxyphenoxy)-
• CAS NO: 1916-04-7
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.247
• Mol File: 1916-04-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(4-methoxyphenoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(4-methoxyphenoxy)-(1916-04-7)
• EPA Substance Registry System: Benzoic acid, 2-(4-methoxyphenoxy)-(1916-04-7)

Safety Data

• Hazardous Substances Data: 1916-04-7(Hazardous Substances Data)

Upstream product

• 150-76-5 4-methoxy-phenol 
• 118-91-2 ortho-chlorobenzoic acid 
• 1122-93-6 potassium p-methoxyphenolate 
• 88-67-5 2-Iodobenzoic acid 
• 16463-38-0 potassium 2-chlorobenzoate 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 171771-88-3 2-(4-methoxy-phenoxy)benzonitrile 
• 394-47-8 2-fluorobenzonitrile 
• 88-65-3 2-bromobenzoic-acid 
• 3235-09-4 potassium o-cresolate 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 101169-35-1 ethyl 2-(4-methoxy-phenoxy)benzoate 
• 1445772-45-1 9-oxo-9H-xanthen-2-yl trifluoromethanesulfonate 
• 109514-82-1 2-hydroxy-N-(4-methoxyphenyl)-N-methylbenzamide 
• 1915-98-6 2-hydroxy-9H-xanthen-9-one 
• 1214-20-6 2-methoxy-9H-xanthen-9-one 
• 10268-61-8 4-methoxyphenyl 2-hydroxybenzoate 
• 25558-61-6 2-(4-Methoxyphenyloxy)-phenylacetic Acid 
• 25563-00-2 2-(4-Methoxy-phenoxy)-phenylacetonitril 
• 25562-96-3 2-(4-Methoxy-phenoxy)-benzylchlorid 
• 124290-17-1 2-benzoyl-3-phenyl-pyrano[3,2-a]xanthene-1,12-dione 
• 101597-66-4 2-(3-acetyl-4-hydroxy-phenoxy)-benzoic acid ethyl ester 
• 100915-09-1 2-(3-acetyl-4-hydroxy-phenoxy)-benzoic acid 
• 152810-93-0 N-(2-Methoxy-9H-xanthen-9-yl) benzyl carbamate 
• 144463-68-3 allyl 2-(4-methoxyphenoxy)benzoate 

Relevant articles and documents

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

Design and development of multitarget-directed ligands (MTDLs) has become a very important approach in the search of new therapies for Alzheimer's disease (AD). In our present research, a number of xanthone derivatives were first designed using a pharmaco

Formal Aniline Synthesis from Phenols through Deoxygenative N-Centered Radical Substitution

Phenolic, lignin-derived substrates have emerged as desirable biorenewable chemical feedstocks for coupling reactions. A radical-mediated conversion of phenol derivatives to anilines is reported, using unfunctionalized hydroxamic acids as the N-centered radical source. The applicability of this triethyl phosphite mediated O-atom transfer approach, which tolerates a range of steric and electronic demands to naturally occurring phenols and lignin models, has been demonstrated in this work to access the corresponding aniline derivatives.

Efficient Aryl Migration from an Aryl Ether to a Carboxylic Acid Group To Form an Ester by Visible-Light Photoredox Catalysis

We have developed a highly efficient aryl migration from an aryl ether to a carboxylic acid group through retro-Smiles rearrangement by visible-light photoredox catalysis at ambient temperature. Transition metals and a stoichiometric oxidant and base are avoided in the transformation. Inspired by the high efficiency of this transformation and the fundamental importance of C?O bond cleavage, we developed a novel approach to the C?O cleavage of a biaryl ether to form two phenolic compounds, as demonstrated by a one-pot, two-step gram-scale reaction under mild conditions. The aryl migration exhibits broad scope and can be applied to the synthesis of pharmaceutical compounds, such as guacetisal. Primary mechanistic studies indicate that the catalytic cycle occurs by a reductive quenching pathway.