191613-07-7

Upstream product

• 179411-51-9 N-(4-((tert-butyldimethylsilyl)oxy)benzylidene)-4-fluoroaniline 
• 191613-06-6 (S)-3-(2-Phenethylsulfanyl-acetyl)-4-phenyl-oxazolidin-2-one 
• 191613-05-5 (S)-3-(2-chloroacetyl)-4-phenyloxazolidin-2-one 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 
• 4410-99-5 2-mercaptophenylethane 
• 371-40-4 4-fluoroaniline 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 

Downstream Products

• 191613-08-8 (3S,4R)-4-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1-(4-fluoro-phenyl)-3-phenethylsulfanyl-azetidin-2-one 
• 191613-37-3 (3R,4R)-4-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-1-(4-fluoro-phenyl)-3-phenethylsulfanyl-azetidin-2-one 
• 179411-33-7 trans-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(2-phenylethyl)-thio]-2-azetidinone 
• 179602-71-2 (3S,4R)-1-(4-Fluoro-phenyl)-4-(4-hydroxy-phenyl)-3-phenethylsulfanyl-azetidin-2-one 

Relevant academic research and scientific papers

Synthesis of C3 heteroatom-substituted azetidinones that display potent cholesterol absorption inhibitory activity

The C3 phenylpropyl side chain N-phenylazetidinones related to SCH 56524 was modified by replacing the hydroxymethylene with various isoelectronic or isosteric groups. Modifications at the 3' position led to less-active compounds; however, modifications a