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CAS

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191667-82-0

1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 191667-82-0 Structure

  • Basic information

    1. Product Name: 1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide
    2. Synonyms: 1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide
    3. CAS NO:191667-82-0
    4. Molecular Formula:
    5. Molecular Weight: 414.934
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 191667-82-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide(191667-82-0)
    11. EPA Substance Registry System: 1-allyl-4-(4-chloro-phenyl)-1H-pyrrole-3-carboxylic acid methyl-naphthalen-1-ylmethyl-amide(191667-82-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 191667-82-0(Hazardous Substances Data)

191667-82-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 191667-82-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,6,6 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 191667-82:
(8*1)+(7*9)+(6*1)+(5*6)+(4*6)+(3*7)+(2*8)+(1*2)=170
170 % 10 = 0
So 191667-82-0 is a valid CAS Registry Number.

191667-82-0Downstream Products

191667-82-0Relevant articles and documents

N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-yl methyl)methylamines related to naftifine. Synthesis and antifungal activity

Di Santo, Roberto,Costi, Roberta,Artico, Marino,Massa, Silvio,Musiu, Chiara,Milia, Carlo,Putzolu, Monica,La Colla, Paolo

, p. 98 - 108 (2007/10/03)

Various pyrrole analogues of the antifungal drug naftifine were prepared starting from cinnamates via the tosylmethylisocyanide (TosMIC) reaction. After alkylation and hydrolysis, the intermediate arylpyrrole esters afforded 1-alkyl-4-aryl-1H-pyrrole-3-carboxylic acids, which were condensed with N-(1-naphthylmethyl)methylamine in the presence of EDCI and triethylamine. The related amides were then reduced with lithium aluminum hydride to the required N-(1-naphthylmethyl)-N-(1-alkyl-4-aryl-1H-pyrrol-3-ylmethyl)methylamines. The new compounds were evaluated for antifungal activity in comparison with naftifine and other imidazole drugs used in the clinic. Derivative 7c was active against Candida parapsilosis and compound 51 against Candida albicans. Weak activity against dermatophytes was shown by a number of derivatives. Moreover, compounds 4g, 4j, 4k and 4p were found active against Staphylococcus aureus with potencies comparable to that of streptomycin.

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