65473-13-4 Usage
Chemical Properties
N-Methyl-1-naphthalenemethylamine hydrochloride is off-white powder
Uses
Different sources of media describe the Uses of 65473-13-4 differently. You can refer to the following data:
1. N-Methyl-1-naphthalenemethanamine hydrochloride is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).
2. N-Methyl-1-naphthalenemethanamine hydrochloride (Terbinafine BP Impurity A; Terbinafine USP Related Compound A) is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).
Check Digit Verification of cas no
The CAS Registry Mumber 65473-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,4,7 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65473-13:
(7*6)+(6*5)+(5*4)+(4*7)+(3*3)+(2*1)+(1*3)=134
134 % 10 = 4
So 65473-13-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N/c1-13-9-11-7-4-6-10-5-2-3-8-12(10)11/h2-8,13H,9H2,1H3/p+1
65473-13-4Relevant articles and documents
Synthesis of potential inhibitors of squalenepoxidase with conformationanl fixation of the structural elements of Butenafine
Stanetty,Wallner
, p. 341 - 350 (2007/10/02)
The synthesis of the naphthalinemethanamines 6b-h is reported. To obtain products with conformative rigidity, substituents with gradually increased space demand were placed into the α-position. Since the direct reductive amination of the naphthylalkanones 3 with the amines 9 or 10 was only of very limited use the α-substituted naphthalinmethanamines 2 and 4 were synthesized as useful intermediates by various methods and the desired N-substitution pattern of the target compounds was subsequently built up applying - mostly reductive - alkylation methods.
