191789-23-8Relevant academic research and scientific papers
Construction of contiguous chiral tertiary carbon centers by enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand
Yasuda, Kosuke,Shindo, Mitsum,Koga, Kenji
, p. 3531 - 3534 (1997)
The diastereo- and enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was examined. Michael adducts (4) were obtained in excellent chemical yields (95~99%) with high stereoselectivities (syn-4/anti-4: 16/84~1/99;
