191793-10-9

Upstream product

• 4381-96-8 (+/-)-1,2,3,4-tetra-O-acetylconduritol E 
• 4782-75-6 conduritol D 
• 17793-95-2 cis-1,2-dihydrocatechol 

Downstream Products

• 594858-32-9 (-)-1,2,3,4-tetra-O-acetylconduritol E 
• 137567-79-4 (1R,2R,3R,4R)-5-cyclohexene-1,2,3,4-tetrol 
• 155239-00-2 (3R,4R,5R,6S)-6-amino-3,4,5-trihydroxy-cyclohex-1-ene 

Relevant academic research and scientific papers

An efficient enzymatic preparation of (+)- and (-)-conduritol E, a cyclitol with C2 symmetry

Lypozyme IM (immobilised lipase from Mucor miehei) catalyses the enantiomeric alcoholysis of tetraacetylconduritol E (±)-2 to give enantiopure (1R,2R,3R,4R)-tetrahydroxycyclohex-5-ene (-)-1, and the unreacted ester (1S,2S,3S,4S)-tetraacetyloxycyclohex-5-ene, (+)-2. The latter was transformed by basic hydrolysis into (+)-1 in high yield and 95% ee. Selective amination of partial ester (-)-3, obtained by short alcoholysis of (±)-2, furnished the previously unreported conduramine F-4, (-)-4.